Crystallin, alpha A (CRYAA) Antikörper

Antigen: Crystallin, alpha A (CRYAA)

Synonyme: CRYA1, HSPB4, Crya1, lop18, Acry-1, Crya-1, DAcry-1, AI323437, cryaa-A, CRYAA, fc06h04, MGC92036, zgc:92036, wu:fc06h04, alpha-a-crystallin

Klonalität: Monoklonal (C9F2)

Wirt: Maus

Reaktivität: Human

Applikation: ELISA, Western Blot (WB)

Produktnummer: ABIN165393

Produktbeschreibung

Weitere Bezeichnung: alpha crystallin A

Immunogen: Recombinant human alpha-Crystallin A protein. Anti-human Crystallin (A mAb, clone c9F2, is derived from hybridization of mouse SP2/O myeloma cells with spleen cells from BALB/c mice immunized with recombinant human Crystallin alphaA.

Isotyp: IgG1 kappa  (Passende Sekundärantikörper)

Klon: C9F2

Beschreibung: Alpha-crystallins, a major protein of the ocular lens, are thought to play a role in maintaining lens transparency, which are composed of two gene products alpha-A and alpha-B, for acidic and basic, respectively. alpha-crystallins can be induced by heat shock and are members of the small heat shock protein (sHSP). They act as molecular chaperones and hold unfolded or misfolded proteins in large, water-soluble low molecular weight aggregates. These heterogeneous aggregates consist of 30-40 subunits of alpha-crystallins, and the alpha-A and alpha-B subunits have a 3:1 ratio, respectively. Two additional functions of alpha-crystallins are an autokinase activity and the participation in the intracellular architecture.

Anwendungen

Applikationshinweise: The antibody has been tested by ELISA and by Western blot analysis

Konzentration: 1mg/ml

Reinigung: The antibody was purified from mouse ascitic fluid by protein-G affinity chromatography. Store at 4C for up to one month. Store at -20C for long term storage. Avoid repeated freezing and thawing.

Buffer: Liquid. Supplied in phosphate buffered saline, pH 7.4 with 0.1% Sodium Azide.

Beschränkungen: Nur für Forschungszwecke einsetzbar