H-2Kq Antikörper (FITC)

Antigen: H-2Kq

Klonalität: Monoklonal (KH114)

Wirt: Maus

Reaktivität: Maus

Konjugat: FITC

Applikation: Durchflusszytometrie (FACS)

Produktnummer: ABIN156709

Produktbeschreibung

Immunogen: B10.Q mouse splenocytes

Isotyp: IgG2a, IgG2a kappa, kappa chain

Klon: KH114

Beschreibung: The KH114 antibody reacts with the H-2K MHC class I alloantigen expressed on nucleated cells from mice of the H-2K haplotype. H-2K is involved in antigen presentation to T cells expressing CD3/TCR and CD8 proteins. The KH114 antibody has not been reported to cross-react with other haplotypes. Distribution: Nucleated cells of the H-2K haplotype Function: Antigen presentation Synonyms: MHC class I Structure: MHC class I

Anwendungen

Applikationshinweise: Additional reported applications (for the relevant formats) include: complement-mediated cytotoxicity. Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is < 1.0 µg per 10 cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.

Reinigung: The antibody was purified by affinity chromatography, and conjugated with FITC under optimal conditions. The solution is free of unconjugated FITC.

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.

Lagerung: The antibody solution should be stored undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Bilder

anti-H-2Kq antibody (FITC)

Publikationen

Publikationen: York, Rock: "Antigen processing and presentation by the class I major histocompatibility complex." in: Annual review of immunology, Vol. 14, pp. 369-96, 1996 (PubMed).

Watts: "Capture and processing of exogenous antigens for presentation on MHC molecules." in: Annual review of immunology, Vol. 15, pp. 821-50, 1997 (PubMed).

Pamer, Cresswell: "Mechanisms of MHC class I--restricted antigen processing." in: Annual review of immunology, Vol. 16, pp. 323-58, 1998 (PubMed).

Kafrouni, Brown, Thiele: "Virally infected hepatocytes are resistant to perforin-dependent CTL effector mechanisms." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 167, Issue 3, pp. 1566-74, 2001 (PubMed).

Nanni, Nicoletti, De Giovanni et al.: "Combined allogeneic tumor cell vaccination and systemic interleukin 12 prevents mammary carcinogenesis in HER-2/neu transgenic mice." in: The Journal of experimental medicine, Vol. 194, Issue 9, pp. 1195-205, 2001 (PubMed).