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CD73 Antikörper (FITC)

NT5E Reaktivität: Human, Non-Human Primate FACS Wirt: Maus Monoclonal AD2 FITC
Produktnummer ABIN1558084
  • Target Alle CD73 (NT5E) Antikörper anzeigen
    CD73 (NT5E) (5'-Nucleotidase, Ecto (CD73) (NT5E))
    Reaktivität
    • 119
    • 59
    • 27
    • 18
    • 18
    • 16
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Non-Human Primate
    Wirt
    • 92
    • 39
    • 17
    • 2
    Maus
    Klonalität
    • 83
    • 67
    Monoklonal
    Konjugat
    • 63
    • 18
    • 13
    • 11
    • 10
    • 6
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CD73 Antikörper ist konjugiert mit FITC
    Applikation
    • 96
    • 64
    • 60
    • 51
    • 20
    • 19
    • 14
    • 14
    • 14
    • 8
    • 7
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    Spezifität
    The mouse monoclonal antibody AD2 recognizes CD73, a 70 kDa GPI-anchored 5´-nucleotidase expressed predominantly on the surface of T and B cell subsets, follicular dendritic cells and endothelial cells.
    Kreuzreaktivität (Details)
    Human
    Aufreinigung
    Purified antibody is conjugated with fluorescein isothiocyanate (FITC) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
    Immunogen
    pre-B leukemia cells
    Klon
    AD2
    Isotyp
    IgG1 kappa
    Top Product
    Discover our top product NT5E Primärantikörper
  • Applikationshinweise
    Flow cytometry: The reagent is designed for analysis of human blood cells using 4 μL reagent / 100 μL of whole blood or 106 cells in a suspension. The content of a vial (0.4 ml) is sufficient for 100 tests.
    Kommentare

    The purified antibody is conjugated with Fluorescein isothiocyanate (FITC) under optimum conditions. The reagent is free of unconjugated FITC and adjusted for direct use. No reconstitution is necessary.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Rekonstitution
    No reconstitution is necessary.
    Buffer
    Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Do not freeze.
    Avoid prolonged exposure to light.
    Lagerung
    4 °C
    Informationen zur Lagerung
    Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
  • Semenov, Koestenbauer, Riegel, Zech, Zimmermann, Zisch, Malek: "Multipotent mesenchymal stem cells from human placenta: critical parameters for isolation and maintenance of stemness after isolation." in: American journal of obstetrics and gynecology, Vol. 202, Issue 2, pp. 193.e1-193.e13, (2010) (PubMed).

    Mokry, Soukup, Micuda, Karbanova, Visek, Brcakova, Suchanek, Bouchal, Vokurkova, Ivancakova: "Telomere attrition occurs during ex vivo expansion of human dental pulp stem cells." in: Journal of biomedicine & biotechnology, Vol. 2010, pp. 673513, (2010) (PubMed).

    Paquet-Fifield, Schlüter, Li, Aitken, Gangatirkar, Blashki, Koelmeyer, Pouliot, Palatsides, Ellis, Brouard, Zannettino, Saunders, Thompson, Li, Kaur: "A role for pericytes as microenvironmental regulators of human skin tissue regeneration." in: The Journal of clinical investigation, Vol. 119, Issue 9, pp. 2795-806, (2009) (PubMed).

    Rodriguez, Paquet, Yang, Erle: "Differential gene expression by integrin beta 7+ and beta 7- memory T helper cells." in: BMC immunology, Vol. 5, pp. 13, (2004) (PubMed).

    Hashikawa, Takedachi, Terakura, Saho, Yamada, Thompson, Shimabukuro, Murakami: "Involvement of CD73 (ecto-5'-nucleotidase) in adenosine generation by human gingival fibroblasts." in: Journal of dental research, Vol. 82, Issue 11, pp. 888-92, (2003) (PubMed).

    Nemoto, Tada, Shimauchi: "Disruption of CD40/CD40 ligand interaction with cleavage of CD40 on human gingival fibroblasts by human leukocyte elastase resulting in down-regulation of chemokine production." in: Journal of leukocyte biology, Vol. 72, Issue 3, pp. 538-45, (2002) (PubMed).

    Borrione, Peola, Mariani, Besostri, Mallone, Malavasi, Pileri, Massaia: "CD38 stimulation lowers the activation threshold and enhances the alloreactivity of cord blood T cells by activating the phosphatidylinositol 3-kinase pathway and inducing CD73 expression." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 162, Issue 10, pp. 6238-46, (1999) (PubMed).

  • Target
    CD73 (NT5E) (5'-Nucleotidase, Ecto (CD73) (NT5E))
    Andere Bezeichnung
    CD73 (NT5E Produkte)
    Synonyme
    CALJA antikoerper, CD73 antikoerper, E5NT antikoerper, NT antikoerper, NT5 antikoerper, NTE antikoerper, eN antikoerper, eNT antikoerper, zgc:63784 antikoerper, NT5E antikoerper, MGC114869 antikoerper, PSPTO2277 antikoerper, 2210401F01Rik antikoerper, AI447961 antikoerper, Nt5 antikoerper, 5'-nucleotidase ecto antikoerper, 5'-nucleotidase, ecto (CD73) antikoerper, 5'-nucleotidase antikoerper, 5' nucleotidase, ecto antikoerper, NT5E antikoerper, nt5e antikoerper, nt5e.S antikoerper, PSPTO_2277 antikoerper, CBU_1233 antikoerper, MCA1322 antikoerper, Nt5e antikoerper
    Hintergrund
    5'-nucleotidase ecto,CD73 (ecto-5´-nucleotidase) is a 70 kDa glycoprotein anchored to the extracellular leaflet of the plasma membrane by GPI. This ecto-enzyme catalyzes dephosphorylation of AMP to adenosine. CD73 is expressed in various types of cells, such as epithelial, muscle, and endothelial cells, neutrophils, lymphocytes and fibroblasts. Inflammatory mediators support CD73 expression and its enzymatic activity, leading to the release of adenosine, which modulates inflammation through adenosine receptors. CD73 is expressed in a variety of lymphomas and leukemias, including ALL and CLL, whereas immunodeficient patients usually express low levels of this protein.,ecto-5´nucleotidase, NT5E, E5NT, CALJA, NTE
    Gen-ID
    4907
    UniProt
    P21589
    Pathways
    Synaptic Membrane, Ribonucleoside Biosynthetic Process
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