Nuclease-Sensitive Element-Binding Protein 1 (YBX1) (N-Term) Antikörper

Antigen: Nuclease-Sensitive Element-Binding Protein 1 (YBX1)

Synonyme: YB1, BP-8, CSDB, DBPB, YB-1, CSDA2, NSEP1, NSEP-1, MDR-NF1, MGC104858, MGC110976, MGC117250

Epitope: N-Term

Klonalität: Polyklonal

Wirt: Kaninchen

Reaktivität: Human

Applikation: Western Blot (WB), Immunhistochemie (IHC)

Produktnummer: ABIN155059

Produktbeschreibung

Weitere Bezeichnung: YB-1 (N-Term)

Gen-ID: 4904

Isotyp: IgG  (Passende Sekundärantikörper)

Beschreibung: Members of Y-box binding protein family all contain a DNA binding domain, called the cold shock domain, comprising of 80 amino acids, which is highly conserved from prokaryotes to eukaryotes. Y-box binding protein-1 (YB-1) is a prototypic member of this f

Anwendungen

Applikationshinweise: WB: 1:1000. IHC (p): 1:50 to 1:200 depending on type of tissue

Konzentration: 2 mg/ml

Reinigung: Affinitiy-purified

Lagerung: Store aliquots at -20 C. Avoid repeated thawing and freezing

Forschungsgebiet: Krebs

Beschränkungen: Nur für Forschungszwecke einsetzbar

Bilder

Western Blot

IHC

Publikationen

Publikationen: Krohn R, Raffetseder U, Bot I et al.: "Y-Box Binding Protein-1 Controls CC Chemokine Ligand-5 (CCL5) Expression in Smooth Muscle Cells and Contributes to Neointima Formation in Atherosclerosis-Prone Mice" in: Circulation, Vol. Epub ahead of print, 2007 (PubMed).

Frye, Halfter, Djudjaj et al.: "Y-box protein-1 is actively secreted through a non-classical pathway and acts as an extracellular mitogen." in: EMBO reports, Vol. 10, Issue 7, pp. 783-9, 2009 (PubMed).

Rauen, Raffetseder, Frye et al.: "YB-1 acts as ligand for Notch-3 receptors and modulates receptor activation." in: The Journal of biological chemistry, 2009 (PubMed).