SUCHTUTORIUM ANZEIGENSuch-Tutorium anzeigen
(Benötigt Flash, öffnet sich in neuem Fenster) Show Tutorial VideoSuch-Tutorium anzeigen
(Benötigt Flash, öffnet sich in neuem Fenster)
Produktdetails

anti-nuclease-sensitive element-binding protein 1 (YBX1) (N-Term) Antikörper

Übersicht

Bild für anti-nuclease-sensitive element-binding protein 1 (YBX1) (N-Term) Antikörper
Antigen: Nuclease-sensitive element-binding protein 1 (YBX1)
Klonalität: Polyklonal
Applikation: Western Blotting (WB), Immunohistochemistry (IHC)
Reaktivität: Human
Wirt: Rabbit
3 Publikationen vorhanden 3 Publikationen vorhanden
Menge: 100ug (200ug/ml) (Produktvarianten)
Preis: 250,00 €   (Zzgl. Versandkosten und MWSt)
Bestellnummer: ABIN155053
Verfügbarkeit: Sofort lieferbar
Bestellhinweis Bestellhinweis
In den Warenkorb

Auf dieser Seite

Produktbeschreibung
Anwendungen
Publikationen
Bilder
Verwandte Produkte
Protokolle

Kundenservice

Technische Anfrage stellen
Produktdetails an Kollegen senden
Datenblatt herunterladen

Produktbeschreibung  » anti-nuclease-sensitive element-binding protein 1 (YBX1) (N-Term) Antikörper

zurück nach oben ^


Antigen Nuclease-sensitive element-binding protein 1 (YBX1)
Gen-ID 4904
Reaktivität Human
Klonalität Polyklonal
Format Affinitiy-purified
Isotyp IgG »Passende Sekundärantikörper
Beschreibung Members of Y-box binding protein family all contain a DNA binding domain, called the cold shock domain, comprising of 80 amino acids, which is highly conserved from prokaryotes to eukaryotes. Y-box binding protein-1 (YB-1) is a prototypic member of this family and was originally isolated as a DNA binding protein recognizing the Y-box sequence within the MHC class II gene promoter region. This box is found in the promoter region of several genes involved in positive regulation of cell cycle, such as proliferating cell nuclear antigen, DNA topoisomerase IIa, DNA-polymerase-alpha and cyclins. Consequently, YB-1 is thought to play crucial roles for cell proliferation and carcinogenesis. YB-1 has been reported to be a prognostic marker of breast cancer, ovarian cancer, lung cancer, thyroid cancer, and synovial sarcoma. These findings indicate the significance of YB-1 for the progression of malignant diseases. Alternative names: BP-8, CSDA2, CSDB, DBPB, MDR-NF1, MGC104858, MGC110976, MGC117250, NSEP-1, NSEP1, YB-1, YB1, YBX1, DNA-binding protein B, Y box-binding protein I, nuclease sensitive element binding protein 1.
Wirt Rabbit

Anwendungen  » anti-nuclease-sensitive element-binding protein 1 (YBX1) (N-Term) Antikörper

zurück nach oben ^


Applikation Western Blotting (WB), Immunohistochemistry (IHC)
» Hier finden Sie 3 Protokolle zu den gelisteten Anwendungen
Applikationshinweise WB: 1:1000. IHC (p): 1:50 to 1:200 depending on type of tissue
Konzentration 200ug/ml
Lagerung Store aliquots at -20 C. Avoid repeated thawing and freezing
Forschungsgebiet Krebs
Beschränkungen Nur für Forschungszwecke einsetzbar

Publikationen  » anti-nuclease-sensitive element-binding protein 1 (YBX1) (N-Term) Antikörper

zurück nach oben ^


Publikationen Krohn R, Raffetseder U, Bot I et al.: "Y-Box Binding Protein-1 Controls CC Chemokine Ligand-5 (CCL5) Expression in Smooth Muscle Cells and Contributes to Neointima Formation in Atherosclerosis-Prone Mice" In: Circulation , Vol. Epub ahead of print, 2007 (PubMed)

Frye, Halfter, Djudjaj et al.: "Y-box protein-1 is actively secreted through a non-classical pathway and acts as an extracellular mitogen." In: EMBO reports , Vol. 10, Issue 7, pp. 783-9, 2009 (PubMed)

Rauen, Raffetseder, Frye et al.: "YB-1 acts as ligand for Notch-3 receptors and modulates receptor activation." In: The Journal of biological chemistry , 2009 (PubMed)

Bilder  » anti-nuclease-sensitive element-binding protein 1 (YBX1) (N-Term) Antikörper

zurück nach oben ^