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PCDHGB2 Antikörper (N-Term)

PCDHGB2 Reaktivität: Human WB Wirt: Kaninchen Polyclonal RB38326 unconjugated
Produktnummer ABIN1539095
  • Target Alle PCDHGB2 Antikörper anzeigen
    PCDHGB2 (Protocadherin gamma Subfamily B, 2 (PCDHGB2))
    Bindungsspezifität
    • 7
    • 6
    • 6
    • 2
    • 1
    AA 160-186, N-Term
    Reaktivität
    • 16
    • 1
    Human
    Wirt
    • 13
    • 4
    Kaninchen
    Klonalität
    • 14
    • 3
    Polyklonal
    Konjugat
    • 7
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser PCDHGB2 Antikörper ist unkonjugiert
    Applikation
    • 17
    • 15
    • 1
    • 1
    Western Blotting (WB)
    Aufreinigung
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This PCDHGB2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 160-186 amino acids from the N-terminal region of human PCDHGB2.
    Klon
    RB38326
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product PCDHGB2 Primärantikörper
  • Applikationshinweise
    WB: 1:1000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    PCDHGB2 Antibody (N-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.
    Haltbarkeit
    6 months
  • Target
    PCDHGB2 (Protocadherin gamma Subfamily B, 2 (PCDHGB2))
    Andere Bezeichnung
    PCDHGB2 (PCDHGB2 Produkte)
    Synonyme
    PCDH-GAMMA-B2 antikoerper, protocadherin gamma subfamily B, 2 antikoerper, PCDHGB2 antikoerper, Pcdhgb2 antikoerper
    Hintergrund
    This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes.
    Molekulargewicht
    100875
    Gen-ID
    56103
    NCBI Accession
    NP_061746, NP_115267
    UniProt
    Q9Y5G2
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