Aflatoxin B1 (AFB1) Antikörper

Antigen: Aflatoxin B1 (AFB1)

Klonalität: Monoklonal (6A10)

Wirt: Maus

Applikation: Immunhistochemie (Gefrierschnitte) (IHC (fro)), Enzyme Immunoassay (EIA), Immunfluoreszenz (IF)

Produktnummer: ABIN153352

Produktbeschreibung

Immunogen: Aflatoxin B1 DNA (against the midazole ring-opened persistent form of the major N-7guanine adduct of AFB1).

Isotyp: IgG1  (Passende Sekundärantikörper)

Klon: 6A10

Beschreibung: Aflatoxin is a naturally occurring mycotoxin produced by two types of mold: Aspergillusflavus and Aspergillus parasiticus. Aspergillus flavus is common and widespread innature and is most often found when certain grains are grown under stressful conditionssuch as drought. At least 13 different types of aflatoxin are produced in nature withaflatoxin B1 considered as the most toxic. Aflatoxin B1 exposure may be a potentialetiological agent in hepatocellular carcinoma. Alternate Names: Anti-AFB1 antibody, Anti-AFB1-AR1 antibody, Anti-Aldoketoreductase 7 antibody.

Spezifität: This antibody is specific for Aflatoxin B1. Species Reactivity: All species. There is no cross-reactivity with other carcinogen-DNA adducts. Localization: Nuclear.

Anwendungen

Applikationshinweise: Immunohistochemistry 1/50-1/100. Positive Controls: human HepG2 liver samples

Konzentration: 1.5 mg/ml

Buffer: Preservative: 0.1% sodium azide.

Lagerung: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze thaw cycles.

Forschungsgebiet: Toxine

Beschränkungen: Nur für Forschungszwecke einsetzbar

Publikationen

Publikationen: Chen, Zhang, Lu et al.: "Aflatoxin B1 DNA adducts in smeared tumor tissue from patients with hepatocellular carcinoma." in: Hepatology (Baltimore, Md.), Vol. 16, Issue 5, pp. 1150-5, 1992 (PubMed).

Zhang, Chen, Lee et al.: "Aflatoxin B1-DNA adducts and hepatitis B virus antigens in hepatocellular carcinoma and non-tumorous liver tissue." in: Carcinogenesis, Vol. 12, Issue 12, pp. 2247-52, 1992 (PubMed).

Ochsner, Bell, OLeary et al.: "Inhibitory effect of REP3123 on toxin and spore formation in Clostridium difficile, and in vivo efficacy in a hamster gastrointestinal infection model." in: The Journal of antimicrobial chemotherapy, Vol. 63, Issue 5, pp. 964-71, 2009 (PubMed).