IKK alpha Antikörper (pSer176)

Produktnummer ABIN1531285

Produktdetails anti-IKK alpha Antikörper

Target: IKK alpha (CHUK) (conserved Helix-Loop-Helix Ubiquitous Kinase (CHUK))

Bindungsspezifität: AA 151-200, pSer176

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IKK alpha Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Spezifität:

IKK-alpha (Phospho-Ser176) /IKK-beta (Phospho-Ser177) Antibody detects endogenous levels of IKK-alpha only when phosphorylated at Ser177.

PhosphorylationH:S176/S177 M:S176/S177 R:S176/S177

Aufreinigung: The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.

Reinheit: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human IKK-alpha around the phosphorylation site of Ser177.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500~1:1000 IHC: 1:50~1:100 ELISA: 1:1000

Kommentare:

Unigene-Number: Hs.198998, Hs.656458 (NCBI Gene Symbol: CHUK)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable at -20°C for at least 1 year.

Haltbarkeit: 12 months

Details zu IKK alpha

Target: IKK alpha (CHUK) (conserved Helix-Loop-Helix Ubiquitous Kinase (CHUK))

Andere Bezeichnung: IKK-alpha (CHUK Produkte)

Synonyme: ikk antikoerper, ikk1 antikoerper, ikka antikoerper, ikkalpha antikoerper, CHUK antikoerper, IKBKA antikoerper, IKK-alpha antikoerper, IKK1 antikoerper, IKKA antikoerper, NFKBIKA antikoerper, TCF16 antikoerper, AI256658 antikoerper, Chuk1 antikoerper, Fbx24 antikoerper, Fbxo24 antikoerper, Ikka antikoerper, zgc:56539 antikoerper, conserved helix-loop-helix ubiquitous kinase S homeolog antikoerper, conserved helix-loop-helix ubiquitous kinase antikoerper, chuk.S antikoerper, CHUK antikoerper, Chuk antikoerper, chuk antikoerper

Hintergrund:

Synonyms: CHUK, Conserved helix-loop-helix ubiquitous kinase, I kappa-B kinase alpha, I-kappa-B kinase 1, IkappaB kinase, IkBKA, IKK-A, IKK-alpha, IKK1, IKKA, Inhibitor of nuclear factor kappa-B kinase alpha subunit, kinase IKK-alpha, NFKBIKA, Nuclear factor NFkapp

NCBI Gene Symbol: CHUK

Molekulargewicht: 84 kDa

Gen-ID: 1147, 3551

OMIM: 600664

UniProt: O15111, O14920

Pathways: PI3K-Akt Signalweg, NF-kappaB Signalweg, RTK Signalweg, T-Zell Rezeptor Signalweg, TLR Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades, BCR Signaling, Ubiquitin Proteasome Pathway, S100 Proteine