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TP53 Apoptosis Effector (PERP) Antikörper

Antigen

TP53 Apoptosis Effector (PERP)

Synonyme THW, KCP1, PIGPC1, KRTCAP1, 1110017A08Rik, dJ496H19.1, RP3-496H19.1, PERP, thw, kcp1, pigpc1, krtcap1, MGC84230, wu:fk24g11, MGC127602, LOC100221212
Klonalität Polyklonal
Wirt
Alternativen

Kaninchen

Reaktivität
Alternativen

Human

Applikation
Alternativen Western Blot (WB)
2 Publikationen vorhanden
Produktnummer ABIN153033
Menge 0.1 mg  (1 mg/ml)
Preis 370,00 €   Zzgl. Versandkosten €20,00 und MWSt
Lieferung nach
Verfügbarkeit Lieferung in 7 bis 10 Werktagen

Produktbeschreibung

Weitere Bezeichnung PERP
Gen-ID 64065
Immunogen Amino acids 37-50 of the human PERP protein.
Beschreibung The p53 tumor suppressor activates either cell cycle arrest or apoptosis in response tocellular stress. A novel gene, PERP, is expressed in a p53-dependent manner and athigh levels in apoptotic cells compared with G(1)-arrested cells. PERP induction islinked to p53-dependent apoptosis and is directly activated by p53. These data suggestthat PERP is a novel effector of p53-dependent apoptosis. Alternate Names: anti-PERP antibody, anti-PERP antibody, anti-TP53 apoptosis effectorantibody,anti-HGNC:17637 antibody, anti-KCP1 antibody, anti-KRTCAP1 antibody, anti-PIGPC1antibody, anti-THW antibody, anti-dJ496H19.1antibody, anti-1110017A08Rik antibody,anti-RP3-496H19.1 antibody, anti-keratinocytes associated protein 1antibody.
Spezifität Reacts with the first extracellular loop of the human PERP protein. Species Reactivity: Cross reacts with Human. Localization: Cell Membrane, desmosome, multi-pass membrane protein.

Anwendungen

Applikationshinweise Suggested working dilutions: Western Blot 1:500 to 1:1000
Konzentration 1 mg/ml
Buffer PBS. Preservative: 0.02% sodium azide.
Lagerung Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze thaw cycles.
Forschungsgebiet Signaltransduktion, Extrazelluläre Matrix, Apoptose/Nekrose
Beschränkungen Nur für Forschungszwecke einsetzbar

Publikationen

Publikationen Attardi, Reczek, Cosmas et al.: "PERP, an apoptosis-associated target of p53, is a novel member of the PMP-22/gas3 family." in: Genes & development, Vol. 14, Issue 6, pp. 704-18, 2000 (PubMed).

Singaravelu, Devalaraja-Narashimha, Lastovica et al.: "PERP, a p53 proapoptotic target, mediates apoptotic cell death in renal ischemia." in: American journal of physiology. Renal physiology, Vol. 296, Issue 4, pp. F847-58, 2009 (PubMed).

Alternativen

Alternativen zu Antigen "TP53 Apoptosis Effector (PERP)", Typ "Antikörper" finden
Wirte Kaninchen (15), Ziege (5)
Reaktivitäten Human (16), Maus (3), Hund (2), Ratte (Rattus) (1)
Applikationen Western Blot (WB) (18), Immunfluoreszenz (IF) (5), Enzyme Immunoassay (EIA) (4), ELISA (3), Immunhistochemie (Paraffinschnitte) (IHC (p)) (2), Dot Blot (Dot) (1), Immunzytochemie (ICC) (1), Immunhistochemie (Gefrierschnitte) (IHC (fro)) (1)