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Antikörper
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anti-TP53 Apoptosis Effector (PERP) Antikörper
TP53 Apoptosis Effector (PERP) Antikörper
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| Synonyme |
THW, KCP1, PIGPC1, KRTCAP1, 1110017A08Rik, dJ496H19.1, RP3-496H19.1, PERP, thw, kcp1, pigpc1, krtcap1, MGC84230, wu:fk24g11, MGC127602, LOC100221212 |
| Klonalität |
Polyklonal |
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Wirt
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Reaktivität
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Applikation
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| Produktnummer |
ABIN153033 |
| Menge |
0.1 mg (1 mg/ml) |
| Preis |
370,00 € Zzgl. Versandkosten €20,00 und MWSt
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| Lieferung nach |
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| Verfügbarkeit |
Lieferung in 7 bis 10 Werktagen |
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Weitere Bezeichnung
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PERP
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Gen-ID
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64065
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Immunogen
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Amino acids 37-50 of the human PERP protein.
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Beschreibung
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The p53 tumor suppressor activates either cell cycle arrest or apoptosis in response tocellular stress. A novel gene, PERP, is expressed in a p53-dependent manner and athigh levels in apoptotic cells compared with G(1)-arrested cells. PERP induction islinked to p53-dependent apoptosis and is directly activated by p53. These data suggestthat PERP is a novel effector of p53-dependent apoptosis. Alternate Names: anti-PERP antibody, anti-PERP antibody, anti-TP53 apoptosis effectorantibody,anti-HGNC:17637 antibody, anti-KCP1 antibody, anti-KRTCAP1 antibody, anti-PIGPC1antibody, anti-THW antibody, anti-dJ496H19.1antibody, anti-1110017A08Rik antibody,anti-RP3-496H19.1 antibody, anti-keratinocytes associated protein 1antibody.
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Spezifität
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Reacts with the first extracellular loop of the human PERP protein. Species Reactivity: Cross reacts with Human. Localization: Cell Membrane, desmosome, multi-pass membrane protein.
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Applikationshinweise
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Suggested working dilutions: Western Blot 1:500 to 1:1000
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Konzentration
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1 mg/ml
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Buffer
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PBS. Preservative: 0.02% sodium azide.
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Lagerung
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Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze thaw cycles.
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Forschungsgebiet
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Signaltransduktion, Extrazelluläre Matrix, Apoptose/Nekrose
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Beschränkungen
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Nur für Forschungszwecke einsetzbar
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Publikationen
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Attardi, Reczek, Cosmas et al.: "PERP, an apoptosis-associated target of p53, is a novel member of the PMP-22/gas3 family." in: Genes & development, Vol. 14, Issue 6, pp. 704-18, 2000 (PubMed).
Singaravelu, Devalaraja-Narashimha, Lastovica et al.: "PERP, a p53 proapoptotic target, mediates apoptotic cell death in renal ischemia." in: American journal of physiology. Renal physiology, Vol. 296, Issue 4, pp. F847-58, 2009 (PubMed).
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Alternativen zu Antigen "TP53 Apoptosis Effector (PERP)", Typ "Antikörper" finden
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Wirte
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Kaninchen (15), Ziege (5)
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Reaktivitäten
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Human (16), Maus (3), Hund (2), Ratte (Rattus) (1)
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Applikationen
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Western Blot (WB) (18), Immunfluoreszenz (IF) (5), Enzyme Immunoassay (EIA) (4), ELISA (3), Immunhistochemie (Paraffinschnitte) (IHC (p)) (2), Dot Blot (Dot) (1), Immunzytochemie (ICC) (1), Immunhistochemie (Gefrierschnitte) (IHC (fro)) (1)
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