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Nuclear Mitotic Apparatus Protein 1 (NUMA1) Antikörper

Antigen

Nuclear Mitotic Apparatus Protein 1 (NUMA1)

Synonyme NUMA, AA764025, AL022610, AU014979, 6720401E04Rik, NUMA1, NuMA, SP-H
Klonalität Polyklonal
Wirt
Alternativen

Kaninchen

Reaktivität
Alternativen

Säugetiere

Applikation
Alternativen Immunfluoreszenz (IF), Immunpräzipitation (IP), Western Blot (WB)
3 Publikationen vorhanden
Produktnummer ABIN152988
Menge 0.1 ml  (Varianten)
Preis 360,00 €   Zzgl. Versandkosten €20,00 und MWSt
Lieferung nach
Verfügbarkeit Lieferung in 7 bis 10 Werktagen

Produktbeschreibung

Weitere Bezeichnung NuMA
Gen-ID 4926
Swiss-Prot Q14980
Immunogen Full-length recombinant human NuMA expressed in insect Sf9 cells using baculovirusexpression system, then purified to near homogeneity prior to immunization.
Format Serum
Beschreibung NuMA (nuclear mitotic apparatus) is a long coil-coiled protein that plays a role in theinterphase and mitosis phases of a cell cycle. In interphase, it has been hypothesizedto play a structural role in the nucleoskeleton that may be important in nuclearorganization and functions. During mitosis, it is associated with spindle microtubuleorganization and chromosome positioning. Therefore, this antibody is useful as a cellcycle marker. Alternate Names: anti-Nuclear Mitotic Apparatus Protein antibody, anti-NUMA 1 antibody, anti-NUMA1antibody, anti-SP H antigen antibody, anti-SP-H antibody, anti-Structural nuclear proteinantibody.
Spezifität This antibody is specific for NuMA. Species Reactivity: Reactive to most mammalian species tested.

Anwendungen

Applikationshinweise Suggested working dilutions: immunofluorescence 1:500,Western Blot 1:1,000
Buffer Preservative: 0.1% Sodium Azide.
Lagerung Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Beschränkungen Nur für Forschungszwecke einsetzbar

Publikationen

Publikationen Gaglio, Saredi, Compton: "NuMA is required for the organization of microtubules into aster-like mitotic arrays." in: The Journal of cell biology, Vol. 131, Issue 3, pp. 693-708, 1995 (PubMed).

Yamauchi, Kiriyama, Kimura et al.: "Herpes simplex virus induces extensive modification and dynamic relocalisation of the nuclear mitotic apparatus (NuMA) protein in interphase cells." in: Journal of cell science, Vol. 121, Issue Pt 12, pp. 2087-96, 2008 (PubMed).

Nguyen, Muenger: "Human papillomavirus E7 protein deregulates mitosis via an association with nuclear mitotic apparatus protein 1." in: Journal of virology, Vol. 83, Issue 4, pp. 1700-7, 2009 (PubMed).

Alternativen

Alternativen zu Antigen "Nuclear Mitotic Apparatus Protein 1 (NUMA1)", Typ "Antikörper" finden
Wirte Kaninchen (28), Maus (4)
Reaktivitäten Maus (22), Ratte (Rattus) (21), Human (12), Hund (2), Pferd (2), Säugetiere (2), Schwein (2), Kaninchen (2), Huhn (1), Rind (Kuh) (1)
Applikationen Immunfluoreszenz (IF) (24), Durchflusszytometrie (FACS) (18), Western Blot (WB) (12), Immunpräzipitation (IP) (7), ELISA (3), Immunhistochemie (Paraffinschnitte) (IHC (p)) (3), ELISA (Detektionsantikörper) (2), Enzyme Immunoassay (EIA) (2), Immunhistochemie (formalinfixierte Schnitte) (IHC (f)) (2), Immunzytochemie (ICC) (1), Immunoelectron Microscopy (IEM) (1), Immunhistochemie (Gefrierschnitte) (IHC (fro)) (1)
Konjugate Alexa Flour 488 (1), Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1), RBITC (1)