Nuclear Receptor Subfamily 1, Group H, Member 2/3 (NR1H2/3) Antikörper

Antigen: Nuclear Receptor Subfamily 1, Group H, Member 2/3 (NR1H2/3)

Synonyme: LXRA, LXR-a, RLD-1, NR1H3, LXR-alpha

Klonalität: Polyklonal

Wirt: Kaninchen

Reaktivität: Huhn, Human, Maus, Ratte (Rattus)

Applikation: Western Blot (WB)

Produktnummer: ABIN152925

Produktbeschreibung

Weitere Bezeichnung: NR1H2 + NR1H3

Gen-ID: 10062, 22259, 58852

Immunogen: A synthetic peptide made to an internal portion of the human LXR protein sequence(between residues 50-150).

Beschreibung: Liver X receptor (LXR) is a protein involved in lipid metabolism. It plays a dual role inhelping the body maintain a healthy balance between fat storage and the burning of fat. Alternate Names: anti-Liver X receptor alpha antibody, anti-Liver X receptor beta antibody, anti-Nuclearreceptor NER antibody, anti-Ubiquitously expressed nuclear receptor antibody,anti-LXRa antibody, anti-LXRb antibody, anti-NER antibody, anti-NERI antibody,anti-NR1H2 antibody, anti-NR1H3 antibody, anti-Nuclear receptor subfamily 1 group Hmember 3 antibody, anti-Oxysterols receptor LXR alpha antibody, anti-Oxysterolsreceptor LXR beta antibody, anti-RIP15 antibody, anti-RLD1 antibody, anti-UNRantibody. Related Diseases: Atherosclerosis, Insulin resistance, Cancer

Spezifität: This antibody is specific for LXR alpha and beta isoforms. Species Reactivity: Reacts with human and monkey. 92% sequence identity with rat and mouse, and 90%sequence identity with chicken protein. Localization: Nuclear (potential).

Anwendungen

Applikationshinweise: Suggested working dilutions: Western Blot 0.5 - 2.0 ug/ml(ECL)

Konzentration: 1.04 mg/ml

Buffer: Tris-glycine and 150mM NaCl. Preservative: 0.05% sodium azide.

Lagerung: Store at 4C. Do not freeze.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Bilder

Detection of LXR in human liver using ABIN152925.

Publikationen

Publikationen: Zhang, Yin, Liao et al.: "NO-1886 upregulates ATP binding cassette transporter A1 and inhibits diet-induced atherosclerosis in Chinese Bama minipigs." in: Journal of lipid research, Vol. 47, Issue 9, pp. 2055-63, 2006 (PubMed).

Qiu, Hill: "Atorvastatin decreases lipoprotein lipase and endothelial lipase expression in human THP-1 macrophages." in: Journal of lipid research, Vol. 48, Issue 10, pp. 2112-22, 2007 (PubMed).

Dang, Liu, Pang et al.: "Suppression of 2,3-oxidosqualene cyclase by high fat diet contributes to liver X receptor-alpha-mediated improvement of hepatic lipid profile." in: The Journal of biological chemistry, Vol. 284, Issue 10, pp. 6218-26, 2009 (PubMed).