LIPG (C-Term) Antikörper

Antigen: LIPG

Epitope: C-Term

Klonalität: Polyklonal

Wirt: Kaninchen

Reaktivität: Human

Applikation: Western Blot (WB)

Produktnummer: ABIN152888

Produktbeschreibung

Weitere Bezeichnung: LIPG (C-term)

Gen-ID: 9388, 16890

Swiss-Prot: Q9Y5X9

Immunogen: A C-terminal synthetic peptide made to the human endothelial lipase protein sequence.

Beschreibung: Endothelial lipase (EL) is a novel member of the lipoprotein lipase gene family. It issynthesized by endothelial cells and functions at the site of synthesis. EL most likelyplays a physiological role in modulating lipoprotein metabolism. Overexpressed EL hasbeen shown to reduce HDL cholesterol levels, whereas an EL deficiency appears to beeffective in elevating HDL cholesterol levels in animals. Alternate Names: Anti-EDL antibody, Anti-EL antibody Endothelial cell-derived lipase antibody, Anti-Endothelial lipase precursor antibody,Anti-lipase endothelial antibody, Anti-LIPG antibody. Related Diseases: Obesity, Atherosclerosis

Spezifität: This antibody is specific for human endothelial lipase. Species Reactivity: This antibody recognizes human endothelial lipase. It does not appear to recognizemurine endothelial lipase. Other species have not been tested. Localization: Secreted.

Anwendungen

Applikationshinweise: Suggested working dilutions: Western Blot 1:500

Konzentration: 1 mg/ml

Buffer: Preservative: Sodium Azide.

Lagerung: Store at 4C. Do not freeze.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Bilder

Human endothelial lipase detected in transfected 293 lysates using ABIN152888 (MW 57 kDa)

Publikationen

Publikationen: Nijstad, Wiersma, Gautier et al.: "Scavenger receptor BI-mediated selective uptake is required for the remodeling of high density lipoprotein by endothelial lipase." in: The Journal of biological chemistry, Vol. 284, Issue 10, pp. 6093-100, 2009 (PubMed).

Wiersma, Gatti, Nijstad et al.: "Hepatic SR-BI, not endothelial lipase, expression determines biliary cholesterol secretion in mice." in: Journal of lipid research, Vol. 50, Issue 8, pp. 1571-80, 2009 (PubMed).