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Antikörper
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anti-Cholinergic Receptor, Muscarinic 1 (CHRM1) Antikörper
Cholinergic Receptor, Muscarinic 1 (CHRM1) Antikörper
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| Synonyme |
M1, HM1, M1R, MGC30125, Chrm-1, mAChR, CHRM1, DKFZp459P0517 |
| Klonalität |
Polyklonal |
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Wirt
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Reaktivität
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Applikation
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| Produktnummer |
ABIN152781 |
| Menge |
0.2 mg (1 mg/ml) |
| Preis |
400,00 € Zzgl. Versandkosten €20,00 und MWSt
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| Lieferung nach |
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| Verfügbarkeit |
Lieferung in 7 bis 10 Werktagen |
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Weitere Bezeichnung
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Muscarinic acetylcholine receptor M1
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Immunogen
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Fusion protein containing amino acids 269-320 from human m1 AChR. This sequence iscompletely conserved in mouse, rat, and bovine protein.
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Beschreibung
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Acetylcholine receptors (AChRs) mediate synaptic transmission at the neuromuscularjunction. The channel-linked AChR that mediates rapid, excitatory actions ofacetylcholine is called nicotinic AChR (nAChR) because it can be activated by nicotine.The non-channel linked AChR that medicates the slow actions of acetylcholine, whichcan be either inhibitory or excitatory, is called muscarinic AChR (mAChR) because itcan be activated by muscarine. The mAChRs are present in neurons of the central andperipheral nervous systems, cardiac and smooth muscle and various exocrine glands.There are 5 subtypes (m1-m5) of the receptor that have a tissue specific pattern ofexpression. The m1 receptor is localized primarily in brain tissue.
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Spezifität
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Detects recombinant mouse Muscarinic Acetylcholine Receptor 1 (m1AChR). Species Reactivity: Cross-reacts with Mouse.Expected to cross-react with Human and Rat due to sequencehomology.Not yet tested in other species.
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Applikationshinweise
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Western Blot: use at a concentration of 2 ug/ml.Optimaldilutions / concentrations should be determined by the end user.By Western blot, thisantibody detects an ~64 kDa protein representing recombinant mouse m1AChR. Thisantibody is not recommended for immunohistochemical procedures.
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Konzentration
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1 mg/ml
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Buffer
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PBS, 1 mg/ml BSA. Preservative: 0.05% Sodium Azide.
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Lagerung
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Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
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Forschungsgebiet
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Neurotransmitter , Hormone, Rezeptoren
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Beschränkungen
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Nur für Forschungszwecke einsetzbar
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