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Cholinergic Receptor, Muscarinic 1 (CHRM1) Antikörper

Antigen

Cholinergic Receptor, Muscarinic 1 (CHRM1)

Synonyme M1, HM1, M1R, MGC30125, Chrm-1, mAChR, CHRM1, DKFZp459P0517
Klonalität Polyklonal
Wirt
Alternativen

Kaninchen

Reaktivität
Alternativen

Rind (Kuh), Human, Maus, Ratte (Rattus)

Applikation
Alternativen Western Blot (WB)
Produktnummer ABIN152781
Menge 0.2 mg  (1 mg/ml)
Preis 400,00 €   Zzgl. Versandkosten €20,00 und MWSt
Lieferung nach
Verfügbarkeit Lieferung in 7 bis 10 Werktagen

Produktbeschreibung

Weitere Bezeichnung Muscarinic acetylcholine receptor M1
Immunogen Fusion protein containing amino acids 269-320 from human m1 AChR. This sequence iscompletely conserved in mouse, rat, and bovine protein.
Beschreibung Acetylcholine receptors (AChRs) mediate synaptic transmission at the neuromuscularjunction. The channel-linked AChR that mediates rapid, excitatory actions ofacetylcholine is called nicotinic AChR (nAChR) because it can be activated by nicotine.The non-channel linked AChR that medicates the slow actions of acetylcholine, whichcan be either inhibitory or excitatory, is called muscarinic AChR (mAChR) because itcan be activated by muscarine. The mAChRs are present in neurons of the central andperipheral nervous systems, cardiac and smooth muscle and various exocrine glands.There are 5 subtypes (m1-m5) of the receptor that have a tissue specific pattern ofexpression. The m1 receptor is localized primarily in brain tissue.
Spezifität Detects recombinant mouse Muscarinic Acetylcholine Receptor 1 (m1AChR). Species Reactivity: Cross-reacts with Mouse.Expected to cross-react with Human and Rat due to sequencehomology.Not yet tested in other species.

Anwendungen

Applikationshinweise Western Blot: use at a concentration of 2 ug/ml.Optimaldilutions / concentrations should be determined by the end user.By Western blot, thisantibody detects an ~64 kDa protein representing recombinant mouse m1AChR. Thisantibody is not recommended for immunohistochemical procedures.
Konzentration 1 mg/ml
Buffer PBS, 1 mg/ml BSA. Preservative: 0.05% Sodium Azide.
Lagerung Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Forschungsgebiet Neurotransmitter , Hormone, Rezeptoren
Beschränkungen Nur für Forschungszwecke einsetzbar

Alternativen

Alternativen zu Antigen "Cholinergic Receptor, Muscarinic 1 (CHRM1)", Typ "Antikörper" finden
Wirte Ziege (5), Kaninchen (5)
Reaktivitäten Human (8), Maus (5), Ratte (Rattus) (5), Hund (2)
Applikationen Western Blot (WB) (9), Enzyme Immunoassay (EIA) (4), ELISA (2), Immunfluoreszenz (IF) (1), Immunhistochemie (Gefrierschnitte) (IHC (fro)) (1)