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Antikörper
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anti-O-Linked N-Acetylglucosamine (GlcNAc) Transferase (UDP-N-Acetylglucosamine:po...
O-Linked N-Acetylglucosamine (GlcNAc) Transferase (UDP-N-Acetylglucosamine:polypeptide-N-Acetylglucosaminyl Transferase) (OGT) Antikörper
| Antigen |
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| Synonyme |
HRNT1, FLJ23071, MGC22921, O-GLCNAC, MGC80426, MGC69550 |
| Klonalität |
Monoklonal (HGAC85) |
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Wirt
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Applikation
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 Alternativen Enzyme Immunoassay (EIA), Immunfluoreszenz (IF), Immunpräzipitation (IP), Western Blot (WB)
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| Produktnummer |
ABIN152767 |
| Menge |
0.1 mg (2 mg/ml) |
| Preis |
400,00 € Zzgl. Versandkosten €20,00 und MWSt
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| Lieferung nach |
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| Verfügbarkeit |
Lieferung in 7 bis 10 Werktagen |
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Weitere Bezeichnung
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O-GlcNAc
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Immunogen
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Heat killed, pepsin treated group A streptococci.
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Isotyp
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IgG3 (Passende Sekundärantikörper)
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Klon
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HGAC85
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Beschreibung
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Many cellular proteins, including nuclear pore, oncogene, cytoskeletal, heat shock, viraland transcription regulatory proteins contain single O-linked N-acetylglucosamine(O-GlcNAc) residues attached to serine or threonine residues. It has been observed thatO-GlcNAc glycosylated proteins tend to be under phosphorylated relative tounglycosylated proteins and that O-GlcNAc bearing proteins tend to be found inmultimeric complexes. This has led to the suggestion that O-GlcNAc glycosylation mayobscure phosphorylation sites and acts as a signaling mechanism or mediator ofsignaling. Alternate Names: anti-O-GlcNAc antibody.
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Spezifität
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Recognizes beta-1,3 linked O-linked N-acetylglucosamine (O-GlcNAc) residues ofstreptococcal group A carbohydrate as well as O-GlcNAc glycosylated proteins. Species Reactivity: All Species.
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Applikationshinweise
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Immunofluorescence: use at 10 ug/ml Western Blot: use at 1 ug/ml By Western blot, thisantibody detects several proteins representing O-GlcNAc glycoproteins.Immunofluorescence staining of O-GlcNAc in cells results in labeling of the nuclearenvelope and pores, nucleolus, and cytoplasm. This staining pattern is consistent withother methods of detecting O-GlcNAc moieties.
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Konzentration
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2 mg/ml
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Buffer
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PBS. Preservative: 0.05% Sodium Azide.
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Lagerung
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Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze thaw cycles.
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Beschränkungen
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Nur für Forschungszwecke einsetzbar
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Alternativen zu Antigen "O-Linked N-Acetylglucosamine (GlcNAc) Transferase (UDP-N-Acetylglucosamine:polypeptide-N-Acetylglucosaminyl Transferase) (OGT)", Typ "Antikörper" finden
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Wirte
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Kaninchen (8), Ziege (7), Maus (2)
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Reaktivitäten
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Human (10), Maus (8), Ratte (Rattus) (6), Hund (5), Huhn (1), Rind (Kuh) (1), Fruchtfliege (Drosophila melanogaster) (1), Schwein (1)
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Applikationen
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Western Blot (WB) (16), Immunhistochemie (Paraffinschnitte) (IHC (p)) (5), ELISA (4), Enzyme Immunoassay (EIA) (4), Immunfluoreszenz (IF) (2), Immunpräzipitation (IP) (2), Immunhistochemie (Gefrierschnitte) (IHC (fro)) (1), Immunhistochemie (IHC) (1)
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Epitope
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C-Term (2)
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