Heat Shock 27kDa Protein 1 (HSPB1) Antikörper

Antigen: Heat Shock 27kDa Protein 1 (HSPB1)

Synonyme: CMT2F, HMN2B, HSP27, HSP28, Hsp25, SRP27, HS.76067, DKFZp586P1322, MKBP, Hs.78846, LOH11CR1K, MGC133245, 27kDa, Hsp27, hsp1, cb153, hsp25, hsp27, zgc:103437, MGC85307, HSPB1, cmt2f, hsp28, hs.76067, MGC147259

Klonalität: Monoklonal (G3-1)

Wirt: Maus

Reaktivität: Human, Maus

Applikation: Enzyme Immunoassay (EIA), Immunpräzipitation (IP), Immunhistochemie (Paraffinschnitte) (IHC (p)), Western Blot (WB)

Produktnummer: ABIN152671

Produktbeschreibung

Weitere Bezeichnung: HSPB1 / HSP27

Gen-ID: 3315, 15507

Immunogen: Partially purified HSP 27 derived from MCF-7 cytosol.

Format: Ascites

Isotyp: IgG1  (Passende Sekundärantikörper)

Klon: G3-1

Beschreibung: Hsp27, also referred to as the Estrogen-Regulated 24K protein and HSP28, is one ofseveral small heat shock proteins (HSP) produced by all organisms studied. Hsp27synthesis is induced by elevated temperature, as well as estrogen in hormoneresponsive cells. Interestingly, human HSP27 also shares greater than 50% homologywith low molecular weight Drosophila HSP',s and mammalian a-crystalline lensprotein. Because of the estrogen responsive nature of Hsp27, this protein has beenstudied extensively in human estrogen responsive tissues such as cervix, endometriumand breast tissue. This work has led to the suggestion that Hsp27 may be a usefulmarker in classifying various hormone sensitive tumors. Alternate Names: anti-28 kDa heat shock protein antibody, anti-CMT2F antibody, anti-DKFZp586P1322antibody, anti-Estrogen regulated 24 kDa protein antibody, anti-Heat shock 25kDaprotein 1 antibody, anti-Heat shock 27kDa protein 1 antibody, anti-Heat shock 28kDaprotein 1 antibody, anti-Heat Shock Protein 27 antibody, anti-Heat shock protein beta 1antibody, anti-Heat Shock Protein27 antibody, anti-HS.76067 antibody, anti-Hsp 25antibody, anti-Hsp 27 antibody, anti-Hsp 28 antibody, anti-Hsp B1 antibody, anti-Hsp25antibody, anti-Hsp28 antibody, anti-HspB1 antibody, anti-SRP27 antibody, anti-Stressresponsive protein 27 antibody.

Spezifität: Species Reactivity: Cross-reacts with Human and Mouse.Not yet tested in other species.

Synonyme: CMT2F, HMN2B, HSP27, HSP28, Hsp25, SRP27, HS.76067, DKFZp586P1322, MKBP, Hs.78846, LOH11CR1K, MGC133245, 27kDa, Hsp27, hsp1, cb153, hsp25, hsp27, zgc:103437, MGC85307, HSPB1, cmt2f, hsp28, hs.76067, MGC147259

Anwendungen

Applikationshinweise: Immunohistochemistry: use at a dilution of 1:500 Western Blot: use at a dilution of 1:500Optimal dilutions / concentrations should be determined by the end user.By Westernblot, this antibody detects an ~24 kDa protein representing HSP 27 in MCF-7 cellextract. Immunohistochemical staining of human cervix results in intense cytoplasmicstaining of the epithelium within the parabasal cell layer.

Buffer: PBS with 0.05% sodium azide. Preservative: 0.05% Sodium Azide

Lagerung: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Beschränkungen: Nur für Forschungszwecke einsetzbar