Laminin, alpha 1 (LAMA1) Antikörper

Antigen: Laminin, alpha 1 (LAMA1)

Synonyme: Lama, AA408497, LAMA, LAMA1

Klonalität: Polyklonal

Wirt: Kaninchen

Reaktivität: Maus, Ratte (Rattus)

Applikation: Immunhistochemie (Gefrierschnitte) (IHC (fro)), Immunhistochemie (Paraffinschnitte) (IHC (p)), Western Blot (WB)

Produktnummer: ABIN152490

Produktbeschreibung

Weitere Bezeichnung: Laminin

Gen-ID: 284217, 16772, 316758

Swiss-Prot: P19137

Immunogen: Laminin isolated from mouse EHS tumor.

Beschreibung: Laminin antibodies are widely used to label blood vessels and basement membranes. Alternate Names: Anti-CLM antibody, Anti-Cutis laxa with marfanoid phenotype antibody, Anti-LAMA 1antibody, Anti-LAMA 2 antibody, Anti-LAMA antibody, Anti-LAMA1 antibody,Anti-LAMA2 antibody, Anti-LAMB 1 antibody, Anti-LAMB antibody, Anti-LAMB1antibody, Anti-LAMC 1 antibody, Anti-LAMC antibody, Anti-LAMC1 antibody,Anti-Laminin A chain antibody, Anti-Laminin alpha 1 antibody, Anti-Laminin alpha 2antibody, Anti-Laminin alpha 2 subunit antibody, Anti-Laminin B1 chain antibody,Anti-Laminin B2 chain antibody, Anti-Laminin beta 1 antibody, Anti-Laminin gamma 1antibody, Anti-Laminin M antibody, Anti-Laminin M chain antibody, Anti-Laminin subunitalpha 1 antibody, Anti-Laminin subunit alpha 2 antibody, Anti-Laminin subunit beta 1antibody, Anti-Laminin subunit gamma 1 antibody, Anti-LAMM antibody, Anti-Merosinantibody, Anti-Merosin congenital muscular dystrophy antibody, Anti-Merosin heavychain antibody, Anti-MGC142015 antibody, Anti-MGC87297 antibody.

Spezifität: This antibody is pan-specific and reacts well with all laminin isoforms tested: laminin-1(alpha-1, beta-1, and gamma-1) and laminin-2 (alpha-2, beta-1, and gamma-1) . Species Reactivity: Human, mouse and rat laminin. Other species have not been tested. Localization: Secreted, Basement membrane, Extracellular matrix.

Anwendungen

Applikationshinweise: Suggested working dilutions: Western Blot 1:100-1:5000,Immunohistochemistry-Paraffin 1:500-1:2000,Immunohistochemistry-Frozen 1:500-1:2000. Positive Controls: Basement membranes (blood vessels of any tissue, tumors, nerve)

Konzentration: 1 mg/ml

Buffer: PBS

Lagerung: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Forschungsgebiet: Neurologie, Angiogenese, Extrazelluläre Matrix

Beschränkungen: Nur für Forschungszwecke einsetzbar

Bilder

Staining of rat spinal cord and dorsal root paraformaldehyde/paraffin-embedded tissue using ABIN152490. Pepsin antigen retrieval was performed on this tissue sample.

Detection of laminin by Western blot using ABIN152490.

Publikationen

Publikationen: Krekoski, Neubauer, Zuo et al.: "Axonal regeneration into acellular nerve grafts is enhanced by degradation of chondroitin sulfate proteoglycan." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 21, Issue 16, pp. 6206-13, 2001 (PubMed).

McDaniel, Rumer, Biroc et al.: "Remodeling of the mammary microenvironment after lactation promotes breast tumor cell metastasis." in: The American journal of pathology, Vol. 168, Issue 2, pp. 608-20, 2006 (PubMed).

Gerin, Bommer, Lidell et al.: "On the role of FOX transcription factors in adipocyte differentiation and insulin-stimulated glucose uptake." in: The Journal of biological chemistry, Vol. 284, Issue 16, pp. 10755-63, 2009 (PubMed).