C1q Antikörper
| Antigen |
|
| Klonalität |
Monoklonal (7H8) |
|
Wirt
|
|
|
Reaktivität
|
|
|
Applikation
|
 Alternativen Immunhistochemie (Gefrierschnitte) (IHC (fro)), Durchflusszytometrie (FACS), Immunpräzipitation (IP), Western Blot (WB)
|
| Produktnummer |
ABIN152428 |
| Menge |
50 µg (0.1 mg/ml) |
| Preis |
400,00 € Zzgl. Versandkosten €20,00 und MWSt
|
| Lieferung nach |
|
| Verfügbarkeit |
Lieferung in 7 bis 10 Werktagen |
|
Immunogen
|
Unfortunately, this information is considered to be commercially sensitive.
|
|
Isotyp
|
IgG1 (Passende Sekundärantikörper)
|
|
Klon
|
7H8
|
|
Beschreibung
|
C1q is a sub-component of the first complement component C1, which is formed by theinteraction of C1q with the tetramer C1s-C1r-C1r-C1s.C1q is a member of a family of soluble collagen-like proteins and is composed of threebasic subunits termed A, B and C (27,550, 25,200, 23,800 Da respectively) whichasociate in the proportion 6 A-B subunits (52, 750 Da) and 3 C-C subunits (47,600 Da),to form whole C1q (459,300 Da). C1q binds to IgG and IgM immune complexes, thisactivates C1r and C1s, which are also bound to C1q and so initiates the classicalpathway of complement activation. Alternate Names: anti-C1QA antibody, anti-Complement C1q subcomponent subunit A antibody,anti-complement component 1 q subcomponent A chain antibody, anti-Complementcomponent 1 q subcomponent alpha polypeptide antibody, anti-complement componentC1q A chain antibody.
|
|
Spezifität
|
Species Reactivity: Cross-reacts with Mouse. Not yet tested in other species. Localization: Cytoplasmic and Secreted.
|
|
Applikationshinweise
|
Suggested working dilutions: flow cytometry / FACS analysis 1/10,immunohistochemistry 1/10,immunoprecipitation 1/10,Western Blot 1/10,Immunohistochemistry-Frozen 1/10
|
|
Konzentration
|
0.1 mg/ml
|
|
Buffer
|
0.1% BSA, PBS. Preservative: 0.02% Sodium Azide.
|
|
Lagerung
|
Store at 4C. Do not freeze.
|
|
Forschungsgebiet
|
Neurologie, Angeborene Immunität, Komplementfaktoren
|
|
Beschränkungen
|
Nur für Forschungszwecke einsetzbar
|
Alternativen zu Antigen "C1q", Typ "Antikörper" finden
|
Wirte
|
Schaf (10), Maus (4), Kaninchen (3), Huhn (2), Ziege (2)
|
|
Reaktivitäten
|
Human (20)
|
|
Applikationen
|
Enzyme Immunoassay (EIA) (9), Immunhistochemie (Gefrierschnitte) (IHC (fro)) (8), Immunodiffusion (ID) (6), Immunfluoreszenz (IF) (4), Western Blot (WB) (4), Durchflusszytometrie (FACS) (3), Immunpräzipitation (IP) (3), Radioimmunoassay (RIA) (2), ELISA (1), Funktionale Studien (Func) (1)
|
|
Konjugate
|
FITC (6), HRP (2)
|
