14-3-3 Pan Antikörper

Antigen: 14-3-3 Pan

Klonalität: Polyklonal

Wirt: Kaninchen

Reaktivität: Human, Maus, Ratte (Rattus), Xenopus laevis

Applikation: Western Blot (WB)

Produktnummer: ABIN152089

Produktbeschreibung

Weitere Bezeichnung: 14-3-3 protein pan

Gen-ID: 10971

Immunogen: Peptide from the C-terminus region of 14-3-3 protein, conjugated to keyhole limpethemocyanin (KLH).

Beschreibung: 14-3-3 proteins are a family of highly conserved proteins that appear to have multipleroles in cell signaling. The proteins are abundantly expressed in the brain and havebeen detected in the cerebrospinal fluid of patients with different neurological disorders. 14-3-3 proteins bind protein ligands that are typically phosphorylated on serine orthreonine residues and regulate the functions of these binding partners by a number ofdifferent mechanisms. The14-3-3 proteins affect a diverse array of cellular processesincluding the cell cycle and transcription, signal transduction and intracellular trafficking.(1-4). Alternate Names: anti-Protein kinase C inhibitor protein 1 antibody, anti-KCIP-1 antibody, anti-14-3-3protein beta/alpha antibody, anti-KCIP 1 antibody, anti-Protein 1054 antibody.

Spezifität: Species Reactivity: Human, mouse, Xenopus, and rat based on 100% antigen sequence homology. Localization: Cytoplasmic.

Anwendungen

Applikationshinweise: Suggested working dilutions: Western Blot 1:1,000

Buffer: 10 mM Hepes (pH7.5), 150 mM NaCl, 100 ug/ml BSA and 50% glycerol

Lagerung: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Bilder

Detection of 14-3-3 protein in 10 ug of rat hippocampal lysate using ABIN152089.