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Antikörper
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anti-X-ray Repair, Complementing Defective, Repair in Chinese Hamster (XRCC5) Anti...
X-ray Repair, Complementing Defective, Repair in Chinese Hamster (XRCC5) Antikörper
| Antigen |
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| Synonyme |
KU80, KUB2, Ku86, NFIV, KARP1, KARP-1, FLJ39089 |
| Klonalität |
Polyklonal |
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Wirt
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Reaktivität
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Applikation
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| Produktnummer |
ABIN151946 |
| Menge |
0.1 mg (1 mg/ml) (Varianten) |
| Preis |
370,00 € Zzgl. Versandkosten €20,00 und MWSt
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| Lieferung nach |
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| Verfügbarkeit |
Lieferung in 7 bis 10 Werktagen |
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Weitere Bezeichnung
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XRCC5 / Ku80 / Ku86
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Gen-ID
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7520, 22596, 363247
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Immunogen
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A synthetic peptide corresponding to residues 323-338 [FSKVDEEQMKYKSEGK] of the80 kDa Ku80 protein.
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Beschreibung
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Telomere length maintenance, an activity essential for chromosome stability andgenome integrity, is regulated by telomerase- and telomere-associated factors. TheDNA repair protein Ku (a heterodimer of Ku70 and Ku80 subunits) associates withmammalian telomeres and contributes to telomere maintenance. The Ku heterodimerfunctions at two kinds of DNA ends: telomeres and double-strand breaks. The role thatKu plays at these two classes of termini must be distinct, because Ku is required foraccurate and efficient joining of double-strand breaks while similar DNA repair eventsare normally prohibited at chromosome ends. Alternate Names: anti-ATP dependent DNA helicase II 80 kDa subunit antibody, anti-ATP dependent DNAhelicase II 86 Kd subunit antibody, anti-CTC box binding factor 85 kDa antibody,anti-CTC85 antibody, anti-CTCBF antibody, anti-DNA repair protein XRCC5 antibody,anti-KARP1 antibody, anti-Ku86 autoantigen related protein 1 antibody, anti-NFIVantibody, anti-Nuclear factor IV antibody, anti-Thyroid lupus autoantigen antibody,anti-TLAA antibody, anti-Xray repair complementing defective repair in Chinese hamstercells 5 antibody.
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Spezifität
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Reacts with residues 323-338 [FSKVDEEQMKYKSEGK] of the 80 kDa Ku80 protein. Sequence is 100% conserved between human, mouse rat and hamster. Species Reactivity: This antibody reacts with human, hamster, rat, and mouse.
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Applikationshinweise
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This antibody has only been tested in Western blot.Recommended working dilution: WB at 1:500 dilution However, the investigator should determine the optimal dilution.
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Konzentration
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1 mg/ml
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Buffer
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0.1 mg in 0.1 ml (1 mg/ml) in PBS containing 0.02% sodium azide.
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Lagerung
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Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze thaw cycles.
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Beschränkungen
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Nur für Forschungszwecke einsetzbar
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Alternativen zu Antigen "X-ray Repair, Complementing Defective, Repair in Chinese Hamster (XRCC5)", Typ "Antikörper" finden
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Wirte
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Maus (32), Kaninchen (20), Ziege (8)
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Reaktivitäten
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Human (54), Maus (6), Affe (5), Hamster (3), Ratte (Rattus) (3), Rind (Kuh) (1)
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Applikationen
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Western Blot (WB) (48), Immunhistochemie (Paraffinschnitte) (IHC (p)) (21), Immunfluoreszenz (IF) (16), Enzyme Immunoassay (EIA) (13), Immunpräzipitation (IP) (8), Immunhistochemie (Gefrierschnitte) (IHC (fro)) (5), Durchflusszytometrie (FACS) (4), ELISA (2)
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Konjugate
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Biotin (2), HRP (1)
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Alternativen 
