Jumonji, AT Rich Interactive Domain 2 (JARID2) Antikörper

Antigen: Jumonji, AT Rich Interactive Domain 2 (JARID2)

Synonyme: JMJ, Jmj, C79929, C79931, jumonji, AI317256, AU045941, JARID2, jarid2, jmj

Klonalität: Polyklonal

Wirt: Kaninchen

Reaktivität: Human, Maus

Applikation: Immunfluoreszenz (IF), Western Blot (WB)

Produktnummer: ABIN151637

Produktbeschreibung

Weitere Bezeichnung: JARID2 / Jumonji

Gen-ID: 3720, 16468

Swiss-Prot: Q92833

Immunogen: A synthetic peptide made to an N-terminal portion of the human jumonji proteinsequence (between residues 1-100).

Beschreibung: Jumonji is a nuclear protein that participates in the negative regulation of cell growth. Itis required for neural tube formation and is essential for normal heart development andfunction. As well, it is a part of a group of proteins characterized by a novel structuralmotif, the JmjC domain, which is implicated in chromatin regulation through histonedemethylation. Alternate Names: anti-JARD2 antibody, anti-Jumonji protein antibody, anti-Jumonji/ARIDdomain-containing protein 2 antibody, anti-JARID2 antibody.

Spezifität: This antibody is specific for jumonji. Species Reactivity: Reacts with mouse and Human. Localization: Nuclear.

Anwendungen

Applikationshinweise: Suggested working dilutions: Western Blot 2 ug/ml (ECL). Positive Controls: E16 mouse brain lysate

Konzentration: 1 mg/ml

Buffer: Tris-glycine and 150mM NaCl. Preservative: 0.05% Na azide.

Lagerung: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze thaw cycles.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Bilder

Detection of jumonji protein in E16 mouse brain lysate using 2ug/ml of ABIN151637.

Publikationen

Publikationen: Shirato, Ogawa, Nakajima et al.: "A jumonji (Jarid2) protein complex represses cyclin D1 expression by methylation of histone H3-K9." in: The Journal of biological chemistry, Vol. 284, Issue 2, pp. 733-9, 2009 (PubMed).