DAF3 Antikörper

Antigen: DAF3

Klonalität: Polyklonal

Wirt: Kaninchen

Reaktivität: Caenorhabditis elegans (C. elegans)

Applikation: Immunpräzipitation (IP), Western Blot (WB)

Produktnummer: ABIN151423

Produktbeschreibung

Weitere Bezeichnung: DAF-3

Swiss-Prot: O17532

Immunogen: A synthetic peptide made to the C-terminus (within residues 700-796) of the C.elegansDAF-3 protein.

Format: Serum

Beschreibung: Signals from TGF-beta superfamily receptors are transduced to the nucleus by Smadproteins, which transcriptionally activate target genes. In Caenorhabditis elegans(C.elegans), defects in a TGF-beta-related pathway cause a reversible developmentalarrest and metabolic shift at the dauer larval stage. DAF-3 transgenes interfere withdauer formation, playing a role in the nucleus. DAF-3 is unique in that it is antagonized,rather than activated, by a TGF-beta pathway. Alternate Names: anti-Abnormal dauer formation protein 3 antibody, anti-isoform c antibody, anti-DAF3antibody, anti-DAF 3 antibody.

Spezifität: Species Reactivity: ABIN151423 can be used to detect C. elegans DAF-3 protein. Localization: Nuclear.

Anwendungen

Applikationshinweise: Western Blot 1:1,000-1:5,000

Buffer: Preservative: 0.05% sodium azide.

Lagerung: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Bilder

anti-DAF3 antibody

Publikationen

Publikationen: Deplancke, Mukhopadhyay, Ao et al.: "A gene-centered C. elegans protein-DNA interaction network." in: Cell, Vol. 125, Issue 6, pp. 1193-205, 2006 (PubMed).