Bacillus Anthracis Lethal Factor (LF) Antikörper

Antigen: Bacillus Anthracis Lethal Factor (LF)

Klonalität: Polyklonal

Wirt: Kaninchen

Applikation: Western Blot (WB)

Produktnummer: ABIN149935

Produktbeschreibung

Weitere Bezeichnung: Bacillus anthracis lethal factor

Immunogen: Synthetic peptide corresponding to amino acids 779-792 of Anthrax LF

Format: Serum

Isotyp: IgG  (Passende Sekundärantikörper)

Beschreibung: Anthrax PA (Protective Antigen) and Anthrax LF (Lethal Factor), along with Anthrax EF (Edema Factor), are toxins produced by Bacillus anthracis. All three of the proteins must be present for toxicity to occur. It begins with the binding of PA to its cell-surface receptor, ATR (Anthrax Toxin Receptor), at which point PA is cleaved and the resulting 63 kD carboxyl-terminal fragment binds to LF and EF. LF is a protease that is known to cleave members of the mitogen-activated protein kinase kinase (MAPKK) family.

Anwendungen

Applikationshinweise: WB: Use at a dilution of 1/1000. Detects a band of approximately 90 kDa. Not tested in other applications. Optimal dilutions/concentrations should be determined by the end user.

Reinheit: Whole Serum

Buffer: Preservative: 0.05% Sodium AzideConstituents: 0.2% gelatin, PBS

Lagerung: Store at 4 C. Aliquot and store at -20 C long-term.

Forschungsgebiet: Bakterien, Gram-positive Bakterien, Toxine, Virologie

Beschränkungen: Nur für Forschungszwecke einsetzbar