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Antikörper
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anti-Interleukin 17A (IL17A) Antikörper
Interleukin 17A (IL17A) Antikörper
| Antigen |
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| Synonyme |
IL17, CTLA8, IL-17, IL-17A, Il17, Ctla8, Ctla-8, IL17F, IL17A, ChIL-17 |
| Klonalität |
Polyklonal |
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Wirt
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Reaktivität
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Applikation
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 Alternativen Enzyme Immunoassay (EIA), Neutralisierung (Neut), Western Blot (WB)
Durchflusszytometrie (FACS) (57), Western Blot (WB) (30), ELISA (23), Enzyme Immunoassay (EIA) (22), Neutralisierung (Neut) (21), Intrazelluläre Durchflusszytometrie (ICFC) (18), ELISA (Detektionsantikörper) (12), ELISPOT (11), ELISA (Fangantikörper) (8), Immunhistochemie (Paraffinschnitte) (IHC (p)) (7), Funktionale Studien (Func) (5), ELISPOT (Fangantikörper) (2), ELISPOT (Detektionsantikörper) (2), Immunfluoreszenz (IF) (2), Immunhistochemie (IHC) (2), Dot Blot (Dot) (1), Immunhistochemie (Gefrierschnitte) (IHC (fro)) (1)
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| Produktnummer |
ABIN149149 |
| Menge |
25 µg (0.1 mg/ml) |
| Preis |
300,00 € Zzgl. Versandkosten €20,00 und MWSt
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| Lieferung nach |
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| Verfügbarkeit |
Lieferung in 7 bis 10 Werktagen |
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Weitere Bezeichnung
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Interleukin-17A (IL17A)
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Immunogen
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Recombinant full length human IL17 protein expressed in E. coli.
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Isotyp
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IgG (Passende Sekundärantikörper)
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Beschreibung
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IL17, also known as CTLA-8, is a T cell-derived hematopoietic cytokine. It was originally cloned from a T cell hybridoma produced by fusion of a mouse cytotoxic T cell clone and a rat T lymphoma. IL17 exhibits multiple biological activities on a variety of cells including: the induction of IL6, IL8 and GCSF production in fibroblasts, the enhancement of surface expression of ICAM-1 in fibroblasts, activation of NF-kappaB and costimulation of T cell proliferation. IL17 is an approximately 16 kDa polypeptide of 136 amino acids. The precursor form of IL17 consists of 155 amino acids. To generate the mature IL17 (136 amino acids), the precursor cleaves a 19 amino acid signal peptide. Human IL17 shows approximately 62.5% amino acid homology to mouse IL17 and 58% amino acid homology to rat IL17.
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Spezifität
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By ELISA, the antibody does not cross-react with other cytokines tested.
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Applikationshinweise
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ELISA: Use at an assay dependent dilution. Neut: Use at an assay dependent dilution. WB: Use at an assay dependent dilution. Predicted molecular weight: 16 kDa. Not tested in other applications. Optimal dilutions/concentrations should be determined by the end user.
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Konzentration
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0.1 mg/ml
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Reinheit
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Immunogen affinity purified
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Buffer
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Preservative: 5% trehalose, Constituents: PBS, pH 7.4
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Forschungsgebiet
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Zytokine, Rezeptoren, Inflammation, Immunologie, Virologie, Krebs
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Beschränkungen
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Nur für Forschungszwecke einsetzbar
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Alternativen zu Antigen "Interleukin 17A (IL17A)", Typ "Antikörper" finden
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Wirte
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Maus (88), Ratte (27), Kaninchen (17), Ziege (4), Huhn (1)
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Reaktivitäten
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Human (104), Maus (34), Ratte (Rattus) (3)
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Applikationen
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Durchflusszytometrie (FACS) (57), Western Blot (WB) (30), ELISA (23), Enzyme Immunoassay (EIA) (22), Neutralisierung (Neut) (21), Intrazelluläre Durchflusszytometrie (ICFC) (18), ELISA (Detektionsantikörper) (12), ELISPOT (11), ELISA (Fangantikörper) (8), Immunhistochemie (Paraffinschnitte) (IHC (p)) (7), Funktionale Studien (Func) (5), ELISPOT (Fangantikörper) (2), ELISPOT (Detektionsantikörper) (2), Immunfluoreszenz (IF) (2), Immunhistochemie (IHC) (2), Dot Blot (Dot) (1), Immunhistochemie (Gefrierschnitte) (IHC (fro)) (1)
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Konjugate
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Biotin (24), Alexa Fluor 647 (9), HRP (8), FITC (7), PE (7), PerCP,Cy5.5 (6), Alexa Fluor 488 (5), Pacific Blue (4), APC (1)
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Epitope
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N-Term (2), AA 20-155 (1), Center (1)
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