Chemokine (C-C Motif) Receptor 9 (CCR9) Antikörper

Antigen: Chemokine (C-C Motif) Receptor 9 (CCR9)

Synonyme: GPR28, CDw199, GPR-9-6, D6, hD6, CCR9, CCR10, CMKBR9, MGC126678, MGC138250

Klonalität: Polyklonal

Wirt: Kaninchen

Reaktivität: Human

Applikation: Immunhistochemie (Paraffinschnitte) (IHC (p))

Produktnummer: ABIN148747

Produktbeschreibung

Weitere Bezeichnung: CDw199 / CCR9

Immunogen: Synthetic peptide conjugated to KLH.

Isotyp: IgG  (Passende Sekundärantikörper)

Beschreibung: The protein encoded by this gene is a member of the beta chemokine receptor family. It is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptors are key regulators of the thymocytes migration and maturation in normal and inflammation conditions. The specific ligand of this receptor is CCL25. It has been found that this gene is differentially expressed by T lymphocytes of small intestine and colon, suggested a role in the thymocytes recruitment and development that may permit functional specialization of immune responses in different segment of the gastrointestinal tract. This gene is mapped to the chemokine receptor gene cluster region. Two alternatively spliced transcript variants have been described.

Anwendungen

Applikationshinweise: IHC-P: Use at a dilution of 1/100-1/200. Not tested in other applications. Optimal dilutions/concentrations should be determined by the end user.

Konzentration: 1 mg/ml

Reinheit: Immunogen affinity purified

Buffer: Preservative: 0.01% Sodium AzideConstituents: PBS. pH 7.7

Lagerung: Store at 4 C. Aliquot and store at -20 C long-term.

Forschungsgebiet: Chemokine, Rezeptoren

Beschränkungen: Nur für Forschungszwecke einsetzbar