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Glial Fibrillary Acidic Protein (GFAP) Antikörper

Antigen

Glial Fibrillary Acidic Protein (GFAP)

Synonyme GFAP, DKFZp459C0729, MGC139638, FLJ45472, AI836096, cb345, gfapl, MGC110485, wu:fb34h11, wu:fk42c12, zgc:110485, etID36982.3, xx:af506734
Klonalität Polyklonal
Wirt
Alternativen

Kaninchen

Reaktivität
Alternativen

Rind (Kuh), Huhn, Katze, Meerschweinchen, Hamster, Human, Affe, Maus, Ratte (Rattus), Schaf

Applikation
Alternativen Immunhistochemie (Gefrierschnitte) (IHC (fro)), Immunhistochemie (Paraffinschnitte) (IHC (p))
Produktnummer ABIN148105
Menge 6 ml  (Varianten)
Preis 280,00 €   Zzgl. Versandkosten €20,00 und MWSt
Lieferung nach
Verfügbarkeit Lieferung in 7 bis 10 Werktagen

Produktbeschreibung

Weitere Bezeichnung GFAP
Immunogen Glial fibrillary acidic protein isolated from cow spinal cord.
Isotyp IgG  (Passende Sekundärantikörper)
Beschreibung Glial fibrillary acidic protein (GFAP) is a member of the class III intermediate filament protein family. It is heavily and specifically expressed in astrocytes and certain other astroglia in the central nervous system, in satellite cells in peripheral ganglia, and in non-myelinating Schwann cells in peripheral nerves. In addition neural stem cells frequently strongly express GFAP. Antibodies to GFAP are therefore very useful as markers of astrocytic cells. In addition many types of brain tumor, presumably derived from astrocytic cells, heavily express GFAP. GFAP is also found in the lens epithelium, Kupffer cells of the liver, in some cells in salivary tumors and has been reported in erythrocytes.
Spezifität In the central nervous system, this antibody stains astrocytes and some groups of ependymal cells. However, in the peripheral nervous system, it stains Schwann cells, satellite cells and enteric glial cells.

Anwendungen

Applikationshinweise This antibody has been pretitered and quality controlled to work allon formalin-fixed paraffin-embedded as well as acetone fixed cryostat tissue sections. No further titration is required. We suggest an incubation period of 30-60 minutes at room temperature. However, depending upon the fixation conditions and the staining system employed, optimal incubation conditions should be determined by the user.
Reinheit Protein A purified
Buffer PBS with sodium azide
Lagerung Store at 4 C. Do not freeze.
Forschungsgebiet Stammzellen, Zytoskelett, Glia Marker, Zell-/Gewebemarker, Neurologie
Beschränkungen Nur für Forschungszwecke einsetzbar

Alternativen

Alternativen zu Antigen "Glial Fibrillary Acidic Protein (GFAP)", Typ "Antikörper" finden
Wirte Maus (185), Kaninchen (96), Huhn (15), Ziege (6), Meerschweinchen (2)
Reaktivitäten Human (203), Ratte (Rattus) (92), Schwein (72), Maus (68), Rind (Kuh) (52), Schaf (25), Huhn (24), Kaninchen (21), Hund (19), Meerschweinchen (16), Säugetiere (13), Katze (12), Affe (6), Hamster (5), Vogel (3), Ziege (3), Caprinae (2), Pferd (1), Primate (1)
Applikationen Western Blot (WB) (193), Immunhistochemie (Paraffinschnitte) (IHC (p)) (132), Immunfluoreszenz (IF) (118), Immunhistochemie (Gefrierschnitte) (IHC (fro)) (92), Immunhistochemie (IHC) (48), Immunpräzipitation (IP) (40), Durchflusszytometrie (FACS) (24), Enzyme Immunoassay (EIA) (23), Immunzytochemie (ICC) (23), ELISA (19), ELISA (Detektionsantikörper) (3), Dot Blot (Dot) (2), Immunhistochemie (formalinfixierte Schnitte) (IHC (f)) (2), ELISA (Fangantikörper) (1), Immunoelectron Microscopy (IEM) (1)
Konjugate Biotin (7), Cy3 (4), HRP (4), Alexa Fluor 488 (2), Alexa Flour 488 (1), Alexa Fluor 350 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1), RBITC (1)
Epitope pSer8 (2), C-Term (1), internal (1)