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Antikörper
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anti-Cyclin-Dependent Kinase Inhibitor 1B (p27, Kip1) (CDKN1B) Antikörper
Cyclin-Dependent Kinase Inhibitor 1B (p27, Kip1) (CDKN1B) Antikörper
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| Synonyme |
KIP1, MEN4, CDKN4, MEN1B, P27KIP1, p27, Rpn4, MGC8644, Kip1, Cdki1b, sb:cb611, wu:fb63g10, wu:fb64g10, wu:fe18e03, CDKN1B |
| Klonalität |
Polyklonal |
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Wirt
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Reaktivität
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Applikation
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| Produktnummer |
ABIN147961 |
| Menge |
50 µg (1 mg/ml) |
| Preis |
420,00 € Zzgl. Versandkosten €20,00 und MWSt
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| Lieferung nach |
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| Verfügbarkeit |
Lieferung in 7 bis 10 Werktagen |
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Weitere Bezeichnung
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CDKN1B / KIP1
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Immunogen
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Synthetic peptide, corresponding to amino acids 1-198 of p27 KIP 1.
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Beschreibung
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Cell cycle progression is regulated by cyclins and their cognate Cdks. p27 KIP 1 is a cell cycle regulatory mitotic inhibitor of cdk activity. p27 KIP 1 is a candidate tumor suppressor gene, and has been proposed to function as a possible mediator of TGF beta induced G1 arrest. p27 KIP 1 is up-regulated in response to antimitogenic stimuli. The increased protein expression of p27 results in cellular arrest by binding to cyclin/Cdk complexes such as cyclin D1/Cdk4.
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Applikationshinweise
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WB: Use at a dilution of 1/2000. Predicted molecular weight: 22 kDa. Not tested in other applications. Optimal dilutions/concentrations should be determined by the end user.
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Konzentration
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1 mg/ml
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Reinheit
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Immunogen affinity purified
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Buffer
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Preservative: NoneConstituents: PBS
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Lagerung
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Store at 4 C. Aliquot and store at -20 C long-term.
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Forschungsgebiet
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Krebs, Zellzyklus
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Beschränkungen
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Nur für Forschungszwecke einsetzbar
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Alternativen zu Antigen "Cyclin-Dependent Kinase Inhibitor 1B (p27, Kip1) (CDKN1B)", Typ "Antikörper" finden
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Wirte
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Kaninchen (61), Maus (20), Ziege (8), Huhn (1)
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Reaktivitäten
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Human (81), Maus (35), Ratte (Rattus) (31), Hund (5), Affe (2), Katze (1), Huhn (1), Rind (Kuh) (1)
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Applikationen
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Western Blot (WB) (75), Immunhistochemie (Paraffinschnitte) (IHC (p)) (38), Immunpräzipitation (IP) (19), Enzyme Immunoassay (EIA) (18), ELISA (10), Immunfluoreszenz (IF) (10), Immunhistochemie (Gefrierschnitte) (IHC (fro)) (9), Immunhistochemie (IHC) (9), ELISA (Detektionsantikörper) (5), Dot Blot (Dot) (3)
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Epitope
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pThr187 (5), internal (2), pSer178 (2), pThr157 (2), pThr198 (2), C-Term (1), T198 (1), pS10 (1), pS178 (1), pSer10 (1), pT157 (1), pT187 (1)
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Alternativen 
