Neurotensin Receptor 2 (NTSR2) Antikörper

Antigen: Neurotensin Receptor 2 (NTSR2)

Synonyme: NT2R, NTRL, NTR2, NTSR2

Klonalität: Polyklonal

Wirt: Kaninchen

Reaktivität: Human

Applikation: Immunhistochemie (Paraffinschnitte) (IHC (p))

Produktnummer: ABIN147009

Produktbeschreibung

Weitere Bezeichnung: Neurotensin receptor type 2

Immunogen: Synthetic peptide (human, unfortunately, the amino acid sequence is considered to be commercially sensitive)

Isotyp: IgG  (Passende Sekundärantikörper)

Beschreibung: The protein encoded by this gene belongs to the G protein-coupled receptor family that activate a phosphatidylinositol-calcium second messenger system. Binding and pharmacological studies demonstrate that this receptor binds neurotensin as well as several other ligands already described for neurotensin NT1 receptor. However, unlike NT1 receptor, this gene recognizes, with high affinity, levocabastine, a histamine H1 receptor antagonist previously shown to compete with neurotensin for low-affinity binding sites in brain. These activities suggest that this receptor may be of physiological importance and that a natural agonist for the receptor may exist.Expression has been documented primarily in the brain.

Anwendungen

Applikationshinweise: IHC-P: Use at a dilution of 1/100-1/200. Not tested in other applications. Optimal dilutions/concentrations should be determined by the end user.

Konzentration: 1 mg/ml

Reinheit: Immunogen affinity purified

Buffer: Preservative: 0.01% Sodium AzideConstituents: PBS. pH 7.7

Lagerung: Store at 4 C. Aliquot and store at -20 C long-term.

Beschränkungen: Nur für Forschungszwecke einsetzbar