T Cell Receptor (TCR) Va 8 Antikörper (Biotin)

Antigen: T Cell Receptor (TCR) Va 8

Klonalität: Polyklonal

Wirt: Ratte

Reaktivität: Maus

Konjugat: Biotin

Applikation: Durchflusszytometrie (FACS)

Produktnummer: ABIN146349

Produktbeschreibung

Immunogen: Unfortunately, this information is considered to be commercially sensitive

Isotyp: IgG2a

Beschreibung: T cell receptors (TCR) recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface of antigen presenting cells (APC). Each T cell receptor is a dimer consisting of one alpha and one beta chain or one delta and one gamma chain. This region represents the germline organization of the T cell receptor beta locus. The beta locus includes V (variable), J (joining), diversity (D), and C (constant) segments. During T cell development, the beta chain is synthesized by a recombination event at the DNA level joining a D segment with a J segment, a V segment is then joined to the D-J gene. The C segment is later joined by splicing at the RNA level.

Spezifität: ABIN146349 recognises the murine V alpha 8 chain of the T cell receptor.

Anwendungen

Applikationshinweise: FACS: Use 5 ul of undiluted antibody to label 10^6 cells in 100 ul. Not tested in other applications. Optimal dilutions/concentrations should be determined by the end user.

Reinheit: Protein G purified

Buffer: Preservative: 0.9% Sodium AzideConstituents: PBS

Lagerung: Store at 4 C. Aliquot and store at -20 C long-term.

Forschungsgebiet: Immunologie, Rezeptoren, Signaltransduktion

Beschränkungen: Nur für Forschungszwecke einsetzbar