T Cell Receptor (TCR) Vb 7 Antikörper

Antigen: T Cell Receptor (TCR) Vb 7

Klonalität: Polyklonal

Wirt: Ratte

Reaktivität: Maus

Applikation: Durchflusszytometrie (FACS)

Produktnummer: ABIN146335

Produktbeschreibung

Immunogen: T-cell lymphoma TK1

Isotyp: IgG2b  (Passende Sekundärantikörper)

Beschreibung: T cell receptors (TCR) recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface of antigen presenting cells (APC). Each T cell receptor is a dimer consisting of one alpha and one beta chain or one delta and one gamma chain. This region represents the germline organization of the T cell receptor beta locus. The beta locus includes V (variable), J (joining), diversity (D), and C (constant) segments. During T cell development, the beta chain is synthesized by a recombination event at the DNA level joining a D segment with a J segment, a V segment is then joined to the D-J gene. The C segment is later joined by splicing at the RNA level.

Spezifität: ABIN146335 reacts with the TCR V beta 7 bearing T cells. Note that TCR V beta 7 may not be present in mouse strains expressing MIS-1a haplotype.

Anwendungen

Applikationshinweise: FACS: Use 5 ul of undiluted antibody to label 1 x 10^6 cells in 100 ul. Not tested in other applications. Optimal dilutions/concentrations should be determined by the end user.

Konzentration: 0.2 mg/ml

Reinheit: Protein A purified

Buffer: Preservative: 0.09% Sodium Azide

Lagerung: Store at 4 C. Aliquot and store at -20 C long-term.

Forschungsgebiet: Immunologie, Rezeptoren, Signaltransduktion

Beschränkungen: Nur für Forschungszwecke einsetzbar