D-Dimer Antikörper

Antigen: D-Dimer

Klonalität: Polyklonal

Wirt: Maus

Reaktivität: Human

Applikation: Enzyme Immunoassay (EIA), Western Blot (WB)

Produktnummer: ABIN146235

Produktbeschreibung

Immunogen: This clone has been derived from hybridization of Sp 2/0 myeloma cells with spleen cells of Balb/c mice immunized with homogenized fibrin clot.

Isotyp: IgG2a  (Passende Sekundärantikörper)

Beschreibung: Fibrinogen is the main protein of blood coagulation system. It consists of two identical subunits that contain three polypeptide chains: alpha, beta and gamma. The process of blood coagulation results in the activation of fibrinogen into fibrin by thrombin and fibrin polymerization. Fibrin clot is then digested by plasmin, and fibrin degradation products of different molecular weights are released into the bloodstream.

Spezifität: Ab10051 is specific for D-dimer and high molecular weight fibrin degradation products. Cross-reaction with D-monomer and fibrinogen.

Anwendungen

Applikationshinweise: ELISA: Use at an assay dependent dilution. IA: Use at an assay dependent dilution. WB: Use at an assay dependent dilution. To be analyzed in sandwich immunoassay, plasma must be diluted with 10 mM Tris/HCl buffer, pH 7.5, containing 1 M NaCl and 0.1 % Tween 20. To avoid non-specific binding, the final NaCl concentration in plasma samples must be 0.5 M or more. Not tested in other applications. Optimal dilutions/concentrations should be determined by the end user.

Reinheit: Protein A purified

Buffer: Preservative: 0.1% Sodium AzideConstituents: PBS. pH 7.4

Beschränkungen: Nur für Forschungszwecke einsetzbar