T Cell Receptor (TCR) Va 8 Antikörper

Antigen: T Cell Receptor (TCR) Va 8

Klonalität: Polyklonal

Wirt: Ratte

Reaktivität: Maus

Applikation: Immunhistochemie (Gefrierschnitte) (IHC (fro)), Durchflusszytometrie (FACS)

Produktnummer: ABIN146232

Produktbeschreibung

Immunogen: V alpha 8 T cell receptor

Format: Supernatant

Isotyp: IgG2a  (Passende Sekundärantikörper)

Beschreibung: T cell receptors (TCR) recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface of antigen presenting cells (APC). Each T cell receptor is a dimer consisting of one alpha and one beta chain or one delta and one gamma chain. This region represents the germline organization of the T cell receptor beta locus. The beta locus includes V (variable), J (joining), diversity (D), and C (constant) segments. During T cell development, the beta chain is synthesized by a recombination event at the DNA level joining a D segment with a J segment, a V segment is then joined to the D-J gene. The C segment is later joined by splicing at the RNA level.

Spezifität: ABIN146232 recognises the V alpha 8 chain of the murine T cell receptor.

Anwendungen

Applikationshinweise: FACS: Use at a dilution of 1/2-1/4. Use 10 ul of the suggested working dilution to label 10^6 cells in 100 ul. IHC-Fr: Use at a dilution of 1/2-1/4. Not tested in other applications. Optimal dilutions/concentrations should be determined by the end user.

Reinheit: Tissue culture supernatant

Buffer: Preservative: 0.2% Sodium AzideConstituents: 5-10% Foetal Calf Serum, Tissue Culture Supernatant, 0.2M Tris HCl. pH 7.4

Lagerung: Store at 4 C. Aliquot and store at -20 C long-term.

Forschungsgebiet: Immunologie, Rezeptoren, Signaltransduktion

Beschränkungen: Nur für Forschungszwecke einsetzbar