Blood Group A Antigen Antikörper

Antigen: Blood Group A Antigen

Klonalität: Polyklonal

Wirt: Maus

Reaktivität: Human

Applikation: Immunhistochemie (Gefrierschnitte) (IHC (fro)), Immunhistochemie (Paraffinschnitte) (IHC (p))

Produktnummer: ABIN145773

Produktbeschreibung

Immunogen: HT-29 Colon Cancer Cell Line.

Isotyp: IgG3

Beschreibung: Blood-group antigens are generally defined as molecules formed by sequential addition of saccharides to the carbohydrate side chains of lipids and proteins detected on erythrocytes and certain epithelial cells. The A, B and H antigens are reported to undergo modulation during malignant cellular transformation. Blood group related antigens represent a group of carbohydrate determinants carried on both glycolipids and glycoproteins. They are usually mucin-type, and are detected on erythrocytes, certain epithelial cells, and in secretions of certain individuals. Sixteen genetically and biosynthetically distinct but inter-related specificities belong to this group of antigens, including A, B, H, Lewis A, Lewis B, Lewis X, Lewis Y, and precursor type 1 chain antigens.

Spezifität: Blood Group Type A (BG2) (Types 1 and 2 chains).

Anwendungen

Applikationshinweise: Immunohistochemistry: use at a dilution of 1/40. Not tested in other applications. Optimal dilutions / concentrations should be determined by the end user. Antigen retrieval is not essential, although may be beneficial.

Reinheit: IgG fraction

Buffer: PBS with 1% BSA and 0.1% sodium azide

Lagerung: Store at 4 C.

Forschungsgebiet: Zell-/Gewebemarker, Blutgruppen-Antigene

Beschränkungen: Nur für Forschungszwecke einsetzbar