Blood Group Antigen B Antikörper

Antigen: Blood Group Antigen B

Klonalität: Polyklonal

Wirt: Maus

Reaktivität: Human

Applikation: Immunhistochemie (Paraffinschnitte) (IHC (p))

Produktnummer: ABIN145152

Produktbeschreibung

Weitere Bezeichnung: Blood Group B Antigen

Immunogen: Mixture of erythrocytes of blood group B and glycoprotein fraction isolated from the saliva of secretors with blood group B.

Format: Supernatant

Isotyp: IgM

Beschreibung: Blood-group antigens are generally defined as molecules formed by sequential addition of saccharides to the carbohydrate side chains of lipids and proteins detected on erythrocytes and certain epithelial cells. The A, B and H antigens are reported to undergo modulation during malignant cellular transformation. Blood group related antigens represent a group of carbohydrate determinants carried on both glycolipids and glycoproteins. They are usually mucin-type, and are detected on erythrocytes, certain epithelial cells, and in secretions of certain individuals. Sixteen genetically and biosynthetically distinct but inter-related specificities belong to this group of antigens, including A, B, H, Lewis A, Lewis B, Lewis X, Lewis Y, and precursor type 1 chain antigens.

Spezifität: This antibody recognizes human blood group B antigens. The specifity of the antibody HEB-29 was confirmed by comparison of specifity and reactivity to standard reagent using >5.000 samples of blood.

Anwendungen

Applikationshinweise: IHC-P: Use at an assay dependant concentration. Suitable for use in agglutination. In agglutination tests, the minimum titre is 1:128 with erythrocytes of blood group B. Not tested in other applications. Optimal dilutions/concentrations should be determined by the end user.

Reinheit: Tissue culture supernatant

Buffer: Preservative: NoneConstituents: Tissue Culture Supernatant

Lagerung: Store at +4 C for 3 months. For long-term storage aliquot and store at -20 C. Avoid freeze/thaw cycles.

Forschungsgebiet: Zell-/Gewebemarker, Blutgruppen-Antigene

Beschränkungen: Nur für Forschungszwecke einsetzbar