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TLR8 Antikörper (C-Term)
TLR8
Reaktivität: Human
IHC (p), EIA
Wirt: Kaninchen
Polyclonal
unconjugated
Produktnummer ABIN1450151
Produktdetails anti-TLR8 Antikörper
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Target
Alle TLR8 Antikörper anzeigen
TLR8
(Toll-Like Receptor 8 (TLR8))
Bindungsspezifität
Alle Epitope für TLR8 Antikörper
C-Term
Reaktivität
Alle Reaktivitäten für TLR8 Antikörper
Human
Wirt
Alle Wirte für TLR8 Antikörper
Kaninchen
Klonalität
Alle Klonalitäten für TLR8 Antikörper
Polyklonal
Konjugat
Alle Konjugate für TLR8 Antikörper
Dieser TLR8 Antikörper ist unkonjugiert
Applikation
Alle Applikationen für TLR8 Antikörper
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
Aufreinigung
Affinity chromatography purified via peptide column
Immunogen
15 amino acid synthetic peptide near the carboxy terminus of human TLR8
Isotyp
IgG
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Alternativen
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Anwendungsinformationen
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Applikationshinweise
Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Konzentration
1.0 mg/mL
Buffer
PBS containing 0.02 % Sodium Azide as preservative
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung
Avoid repeated freezing and thawing.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Details zu TLR8
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Target
TLR8
(Toll-Like Receptor 8 (TLR8))
Andere Bezeichnung
CD288 / TLR8 (TLR8 Produkte )
Synonyme
CD288 antikoerper, toll like receptor 8 antikoerper, toll-like receptor 8 antikoerper, TLR8 antikoerper, Tlr8 antikoerper
Hintergrund
Toll-like receptors (TLRs) are signaling molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. These proteins act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors. Like TLR7, TLR8 is localized to endosomal or lysosomal compartments and stimulates the innate immune response after activation by guanosine- and uridine-rich single-stranded RNA. Human but not murine TLR8 confers responsiveness to the antiviral compound R-848.Synonyms: Toll-like receptor 8, UNQ249/PRO286
Gen-ID
51311
NCBI Accession
NP_619542
Pathways
TLR Signalweg , Activation of Innate immune Response , Toll-Like Receptors Cascades
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