SPINK2 Antikörper (C-Term)

Produktnummer ABIN1450114

Produktdetails anti-SPINK2 Antikörper

Target: SPINK2 (serine Peptidase Inhibitor, Kazal Type 2 (Acrosin-Trypsin Inhibitor) (SPINK2))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SPINK2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Kreuzreaktivität (Details): Species reactivity (tested):Human, Mouse.

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: 16 amino acid synthetic peptide near the carboxy terminus of Human SPINK2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % Sodium Azide as preservative

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Referenzen für anti-SPINK2 Antikörper (ABIN1450114)

Dietz, Maes, Huang, Yandell, Schlamp, Montgomery, Allingham, Hauser, Nickells: "Spink2 modulates apoptotic susceptibility and is a candidate gene in the Rgcs1 QTL that affects retinal ganglion cell death after optic nerve damage." in: PLoS ONE, Vol. 9, Issue 4, pp. e93564, (2014) (PubMed).

Details zu SPINK2

Target: SPINK2 (serine Peptidase Inhibitor, Kazal Type 2 (Acrosin-Trypsin Inhibitor) (SPINK2))

Andere Bezeichnung: SPINK2 (SPINK2 Produkte)

Synonyme: 1700007F22Rik antikoerper, AV038945 antikoerper, HUSI-II antikoerper, serine peptidase inhibitor, Kazal type 2 antikoerper, serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) antikoerper, Spink2 antikoerper, SPINK2 antikoerper

Hintergrund: Human serine proteinase inhibitor Kazal-type 2 (SPINK2) is required for maintaining normal spermatogenesis and potentially regulates serine protease-mediated apoptosis in male germ cells. It contains a typical kazal domain composed by six cysteine residues forming three disulfide bridges. SPINK2 functions as a trypsin/acrosin inhibitor and is synthesized mainly in the testis and seminal vesicle where its activity is engaged in fertility. SPINK2 plays a role in the pathogenesis of hereditary and chronic pancreatitis.Synonyms: Acrosin-trypsin inhibitor, HUSI-II, Serine protease inhibitor Kazal-type 2

Gen-ID: 6691

NCBI Accession: NP_065804