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ATG2B Antikörper (N-Term)

ATG2B Reaktivität: Human WB, EIA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN1449993
  • Target Alle ATG2B Produkte
    ATG2B (Autophagy Related 2B (ATG2B))
    Bindungsspezifität
    • 14
    • 10
    • 5
    • 1
    • 1
    • 1
    N-Term
    Reaktivität
    • 26
    • 10
    • 2
    Human
    Wirt
    • 26
    Kaninchen
    Klonalität
    • 26
    Polyklonal
    Konjugat
    • 12
    • 4
    • 3
    • 3
    • 2
    • 2
    Dieser ATG2B Antikörper ist unkonjugiert
    Applikation
    • 20
    • 16
    • 2
    • 2
    • 2
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    Aufreinigung
    Affinity chromatography purified via peptide column
    Immunogen
    A 19 amino acid synthetic peptide near the amino terminus of Human ATG2B
    Isotyp
    IgG
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    1.0 mg/mL
    Buffer
    PBS containing 0.02 % Sodium Azide as preservative
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target
    ATG2B (Autophagy Related 2B (ATG2B))
    Andere Bezeichnung
    ATG2B (ATG2B Produkte)
    Synonyme
    C14orf103 antikoerper, 2410024A21Rik antikoerper, AI047755 antikoerper, AI503411 antikoerper, AW558123 antikoerper, C030004M05Rik antikoerper, C630028L02Rik antikoerper, mKIAA4067 antikoerper, autophagy related 2B antikoerper, ATG2B antikoerper, Atg2b antikoerper
    Hintergrund
    Autophagy, the process of bulk degradation of cellular proteins through an autophagosomic-lysosomal pathway is important for normal growth control and may be defective in tumor cells. It is involved in the preservation of cellular nutrients under starvation conditions as well as the normal turnover of cytosolic components. This process is negatively regulated by TOR (Target of rapamycin) through phosphorylation of autophagy protein APG1. Another member of the autophagy family of proteins is ATG2B, one of two homologs of ATG2 that is essential for autophagosome formation and important for regulation of size and distribution of lipid droplets. Relatively high rates of ATG2B mutations were observed in gastric and colorectal carcinomas, suggesting that deregulating the autophagy process may contribute to cancer development.Synonyms: Autophagy related 2 homolog B
    Molekulargewicht
    229 kDa
    Gen-ID
    55102
    NCBI Accession
    NP_060506
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