SARM1 Antikörper (N-Term)

Produktnummer ABIN1449950

Produktdetails anti-SARM1 Antikörper

Target: SARM1 (Sterile alpha and TIR Motif Containing 1 (SARM1))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SARM1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Kreuzreaktivität (Details): Species reactivity (tested):Human, Mouse, Rat.

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: 16 amino acid synthetic peptide near the amino terminus of Human SARM

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % Sodium Azide as preservative

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu SARM1

Target: SARM1 (Sterile alpha and TIR Motif Containing 1 (SARM1))

Andere Bezeichnung: SARM1 (SARM1 Produkte)

Synonyme: A830091I15Rik antikoerper, C78606 antikoerper, MyD885 antikoerper, Sarm antikoerper, MyD88-5 antikoerper, SAMD2 antikoerper, SARM antikoerper, sterile alpha and TIR motif containing 1 antikoerper, sterile alpha and HEAT/Armadillo motif containing 1 antikoerper, SARM1 antikoerper, Sarm1 antikoerper, sarm1 antikoerper

Hintergrund: Toll-like receptors (TLRs) are signaling molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. SARM (SAM and ARM-containing protein), along with other molecules such as TIRP, TRIF, TIRAP, and MyD88, is thought to serve as an adaptor protein for the TLRs that allows for the activation of downstream kinases and NF-kB, and ultimately the expression of proteins involved in host defense. While SARM has not been conclusively shown to associate directly with TLRs, the presence of a Toll-interleukin-1 (TIR) domain in SARM is consistent with a role as a signaling molecule.Synonyms: KIAA0524, SAM domain-containing protein 2, SAMD2, SARM, Sterile alpha and Armadillo repeat protein, Sterile alpha and TIR motif-containing protein 1, Sterile alpha motif domain-containing protein 2

Gen-ID: 23098

NCBI Accession: NP_055892

Pathways: TLR Signalweg, Activation of Innate immune Response, Toll-Like Receptors Cascades