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FOXP3 Antikörper

FOXP3 Reaktivität: Maus WB Wirt: Ratte Monoclonal MF-14 unconjugated
Produktnummer ABIN1449247
  • Target Alle FOXP3 Antikörper anzeigen
    FOXP3 (Forkhead Box P3 (FOXP3))
    Reaktivität
    • 165
    • 120
    • 51
    • 25
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Maus
    Wirt
    • 116
    • 68
    • 14
    • 2
    Ratte
    Klonalität
    • 116
    • 84
    Monoklonal
    Konjugat
    • 91
    • 18
    • 13
    • 12
    • 12
    • 7
    • 5
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Dieser FOXP3 Antikörper ist unkonjugiert
    Applikation
    • 134
    • 95
    • 70
    • 39
    • 38
    • 27
    • 27
    • 19
    • 18
    • 17
    • 9
    • 8
    • 7
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Spezifität
    This antibody reacts with mouse Foxp3.
    Aufreinigung
    Protein G agarose
    Immunogen
    Recombinant full-length mouse Foxp3
    Klon
    MF-14
    Isotyp
    IgG2b
    Top Product
    Discover our top product FOXP3 Primärantikörper
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    1.0 mg/mL
    Buffer
    PBS containing 50 % glycerol, pH 7.2. No preservative is contained.
    Konservierungsmittel
    Without preservative
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Upon receipt, store (in aliqouts) at -20 °C.
  • Target
    FOXP3 (Forkhead Box P3 (FOXP3))
    Andere Bezeichnung
    FOXP3 (FOXP3 Produkte)
    Synonyme
    foxp3 antikoerper, FOXP3 antikoerper, AIID antikoerper, DIETER antikoerper, IPEX antikoerper, PIDX antikoerper, XPID antikoerper, JM2 antikoerper, scurfin antikoerper, sf antikoerper, RGD1562112 antikoerper, forkhead box P3 antikoerper, forkhead box P3a antikoerper, forkhead box P3 L homeolog antikoerper, FOXP3 antikoerper, foxp3a antikoerper, foxp3 antikoerper, foxp3.L antikoerper, Foxp3 antikoerper
    Hintergrund
    Forkhead-winged helix P3 (Foxp3), also known as Scurfin or JM2, is a 50-55 kDa transcription factor, originally identified as the gene defective in Scurfy mice. Scurfy mice and humans with similar mutations spontaneously develop autoimmune diseases (IPEX). Resent reports revealed that Foxp3 is expressed in CD4 + CD25 + regulatory T cells (Treg cells), and ectopic expression of Foxp3 in CD4 + Foxp3 - T cells induced a Treg-like phenotype in these cells. Importantly, these reports indicate that Foxp3 is a specific marker for Treg cells. Taken together, Foxp3 is believed to be a crucial regulator of the development and function of Treg cells.Synonyms: Forkhead box protein P3, IPEX, JM2, Scurfin
    Gen-ID
    20371
    NCBI Accession
    NP_001186276
    UniProt
    Q99JB6
    Pathways
    Chromatin Binding, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Activated T Cell Proliferation
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