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CYBA Antikörper (PE)

CYBA Reaktivität: Human, Affe FACS Wirt: Maus Monoclonal 7D5 PE
Produktnummer ABIN1449195
  • Target Alle CYBA Antikörper anzeigen
    CYBA (Cytochrome B-245, alpha Polypeptide (CYBA))
    Reaktivität
    • 44
    • 19
    • 19
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Affe
    Wirt
    • 40
    • 4
    Maus
    Klonalität
    • 40
    • 4
    Monoklonal
    Konjugat
    • 15
    • 6
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CYBA Antikörper ist konjugiert mit PE
    Applikation
    • 35
    • 21
    • 17
    • 13
    • 13
    • 5
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    Flow Cytometry (FACS)
    Spezifität
    This antibody recognizes the extracellular peptide portion of primate gp91phox of the Flavocytochrome b558.
    Keine Kreuzreaktivität
    Maus
    Kreuzreaktivität (Details)
    Species reactivity (tested):Human, Monkey.
    Aufreinigung
    Protein A agarose
    Immunogen
    Human cytochrome b-rich fraction
    Klon
    7D5
    Isotyp
    IgG1
    Top Product
    Discover our top product CYBA Primärantikörper
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    PBS, 0.09 % NaN3, 1 % BSA
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C
    Informationen zur Lagerung
    Store at 2-8 °C.
  • Target
    CYBA (Cytochrome B-245, alpha Polypeptide (CYBA))
    Andere Bezeichnung
    Cytochrome B-245 Light Chain (CYBA Produkte)
    Synonyme
    zgc:66077 antikoerper, MGC80750 antikoerper, CYBA antikoerper, p22-phox antikoerper, p22phox antikoerper, p22-PHOX antikoerper, b558 antikoerper, nmf333 antikoerper, P22-PHOX antikoerper, cytochrome b-245, alpha polypeptide antikoerper, cytochrome b-245 alpha polypeptide L homeolog antikoerper, cytochrome b-245 alpha polypeptide antikoerper, cytochrome b-245 light chain-like antikoerper, cytochrome b-245 alpha chain antikoerper, p22-phox antikoerper, cyba antikoerper, cyba.L antikoerper, CYBA antikoerper, LOC101328418 antikoerper, Cyba antikoerper
    Hintergrund
    The NADPH oxidase is a multicomponent enzyme that transfers electrons from NADPH to O2 to generate superoxide (O2 -), a key part of the phagocytic or neutrophilic respiratory burst response. Flavocytochrome b558 is the catalytic component of the phagocyte NADPH oxidase. It is a transmembrane heterodimer composed of a large glycoprotein, gp91phox (PHagocyte OXidase) and a smaller protein, p22phox. Upon cell stimulation, flavocytochrome b558 assembles with p67phox, p47phox, and the GTP-binding protein Rac and becomes activated to generate O2 -. Mutations in gp91phox, p22phox, or other components of the NADPH oxidase can result in chronic granulomatous disease, which is associated with significant morbidity and mortality due to a predisposition to recurrent bacterial and fungal infections.Synonyms: CYBA, Cytochrome b(558) alpha chain, Cytochrome b558 subunit alpha, Neutrophil cytochrome b 22 kDa polypeptide, Superoxide-generating NADPH oxidase light chain subunit, p22 phagocyte B-cytochrome, p22-phox
    Gen-ID
    1535
    NCBI Accession
    NP_000092
    UniProt
    P13498
    Pathways
    Regulation of Systemic Arterial Blood Pressure by Hormones, Carbohydrate Homeostasis
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