EHMT2 Antikörper (C-Term)

Produktnummer ABIN1449182

Produktdetails anti-EHMT2 Antikörper

Target: EHMT2 (Ankyrin Repeat-Containing Protein (EHMT2))

Bindungsspezifität: AA 621-1000, C-Term

Reaktivität: Human, Maus

Wirt: Hamster

Klonalität: Monoklonal

Konjugat: Dieser EHMT2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Spezifität: This antibody reacts with both the 165 kDa G9a-L isoform and the 140 kDa G9a-S isoform.

Kreuzreaktivität (Details): Species reactivity (tested):Human, Mouse

Aufreinigung: Protein A agarose

Immunogen: GST-mouse G9a C-terminal protein (a.a. 621-1000)

Klon: 01-01-14

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS containing 50 % glycerol, pH 7.2. Contains no preservatives.

Konservierungsmittel: Without preservative

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu EHMT2

Target: EHMT2 (Ankyrin Repeat-Containing Protein (EHMT2))

Andere Bezeichnung: BAT8 (EHMT2 Produkte)

Synonyme: BAT8 antikoerper, C6orf30 antikoerper, G9A antikoerper, GAT8 antikoerper, KMT1C antikoerper, NG36 antikoerper, T27C4.12 antikoerper, T27C4_12 antikoerper, DL3235W antikoerper, FCAALL.188 antikoerper, T18B16.120 antikoerper, T18B16_120 antikoerper, F9H3.13 antikoerper, F9H3_13 antikoerper, F9H3.7 antikoerper, F9H3_7 antikoerper, F9H3.9 antikoerper, F9H3_9 antikoerper, F9H3.6 antikoerper, F9H3_6 antikoerper, F13G24.40 antikoerper, T20K14.110 antikoerper, T20K14_110 antikoerper, MWD22.10 antikoerper, MWD22_10 antikoerper, MRB17.12 antikoerper, MRB17_12 antikoerper, MAF19.22 antikoerper, MAF19_22 antikoerper, Bat8 antikoerper, D17Ertd710e antikoerper, G9a antikoerper, Ng36 antikoerper, euchromatic histone lysine methyltransferase 2 antikoerper, ankyrin repeat-containing protein antikoerper, Ankyrin repeat family protein antikoerper, euchromatic histone lysine N-methyltransferase 2 antikoerper, EHMT2 antikoerper, ank1 antikoerper, IscW_ISCW006888 antikoerper, Arnit_2917 antikoerper, AT3G04470 antikoerper, AT4G14390 antikoerper, AT4G19150 antikoerper, AT4G03500 antikoerper, AT4G03450 antikoerper, AT4G03460 antikoerper, AT4G03440 antikoerper, PIA1 antikoerper, AT5G15500 antikoerper, AT5G51160 antikoerper, AT5G54620 antikoerper, ANK6 antikoerper, AT1G04780 antikoerper, AT1G62050 antikoerper, Ehmt2 antikoerper

Hintergrund: G9a (BAT8, NG36) is a major histone methyltransferase that acts by adding a methyl group to the Lys9 amino acid on histone H3 proteins. Methylation of Lys9 on histone H3 is important for the regulation of the expression of crucial genes during embryogenesis. Methylation of Lys9 may also play a role in tumorigenesis, since deregulation of histone H3 Lys9 methylation in G9a-deficient cells induces the expression of Mage-2a, a tumor-specific protein whose function is unknown. The 165 kDa G9a protein has an unusual structure, containing 24 contiguous glutamate residues in the N-terminus and 6 contiguous copies of a 33-amino acid ankyrin repeat in the C-terminus. The presence of the ankyrin repeats suggest that G9a may be involved in intracellular protein-protein interactions. G9a is expressed in monocytic, macrophage, hepatocyte, T-cell, B-cell, epithelial, and promyelocytic cell lines.Synonyms: C6orf30, EHMT2, Euchromatic histone-lysine N-methyltransferase 2, H3 lysine-9 specific 3, H3-K9-HMTase 3, HLA-B-associated transcript 8, Histone H3-K9 methyltransferase 3, Histone-lysine N-methyltransferase, KMT1C, Lysine N-methyltransferase 1C, NG36, Protein G9A

Gen-ID: 110147

NCBI Accession: NP_665829

UniProt: Q9Z148