S-100 Antikörper
| Antigen |
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| Klonalität |
Polyklonal |
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Wirt
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Reaktivität
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Applikation
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 Alternativen Immunhistochemie (Gefrierschnitte) (IHC (fro)), Immunhistochemie (Paraffinschnitte) (IHC (p))
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| Produktnummer |
ABIN141284 |
| Menge |
6 ml (Varianten) |
| Preis |
390,00 € Zzgl. Versandkosten €20,00 und MWSt
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| Lieferung nach |
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| Verfügbarkeit |
Lieferung in 7 bis 10 Werktagen |
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Weitere Bezeichnung
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S100
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Immunogen
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Bovine brain S-100
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Beschreibung
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S100 belongs to the family of calcium binding proteins such as calmodulin and troponin C. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. S100A is composed of an alpha and beta chain whereas S100B is composed of two beta chains. S100 protein may function in stimulation of Ca2+ induced Ca2+ release, inhibition of microtubule assembly, and inhibition of protein kinase C mediated phosphorylation. Reduced expression of this protein has been implicated in cardiomyopathies. Immunoreactive S100 protein localizes in the cytoplasm and nuclei of astrocytes, Schwanns cells, ependymomas and astrogliomas. Ganglion cells do not stain for S100 protein. S100 can be detected in almost all benign naevi and malignant melanocytic tumours of the skin, and in Lang
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Spezifität
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This polyclonal antibody reacts with human S-100 A and S-100 B. This protein is present in brain glial cells and in ependymal cells. Also stains Schwann cells of the peripheral nervous system.
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Applikationshinweise
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For IHC-Fr: Use at a neat dilution. For IHC-P: Use at a neat dilution. Not tested in other applications. Optimal dilutions/concentrations should be determined by the researcher.
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Reinheit
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Ig fraction
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Buffer
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Phosphate buffered saline pH7.4 containing 0.09% sodium azide and 1% BSA
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Lagerung
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Keep as concentrated solution. Store at 4?C short term. For extended storage aliquot and store at -20?C or below. Avoid freeze-thaw cycles.
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Forschungsgebiet
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Zellzyklus
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Beschränkungen
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Nur für Forschungszwecke einsetzbar
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Alternativen zu Antigen "S-100", Typ "Antikörper" finden
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Wirte
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Kaninchen (33), Maus (21), Ziege (1)
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Reaktivitäten
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Human (42), Rind (Kuh) (29), Maus (20), Ratte (Rattus) (20), Affe (11), Huhn (1), Känguruh (1)
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Applikationen
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Immunhistochemie (Paraffinschnitte) (IHC (p)) (36), Immunhistochemie (Gefrierschnitte) (IHC (fro)) (20), Immunhistochemie (IHC) (13), Western Blot (WB) (11), Durchflusszytometrie (FACS) (6), Immunfluoreszenz (IF) (6), Enzyme Immunoassay (EIA) (4), ELISA (3), Immunzytochemie (ICC) (2), To be determined by user (TBD) (2)
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Konjugate
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FITC (4)
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