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Antikörper
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anti-Death Effector Domain Containing 2 (DEDD2) Antikörper
Death Effector Domain Containing 2 (DEDD2) Antikörper
| Antigen |
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| Synonyme |
FLAME-3, DEDD2, MGC140424, MGC145883, DEFT, KE05, DEDD1, FLDED1, CASP8IP1, 2410050E11Rik, DEDD, MGC127710, DKFZp459K109 |
| Klonalität |
Polyklonal |
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Wirt
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Applikation
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Durchflusszytometrie (FACS) (17), Immunfluoreszenz (IF) (16), Western Blot (WB) (13), Immunhistochemie (Paraffinschnitte) (IHC (p)) (5), Immunpräzipitation (IP) (4), ELISA (3), Immunhistochemie (Gefrierschnitte) (IHC (fro)) (3), Dot Blot (Dot) (1), Enzyme Immunoassay (EIA) (1), Immunoelectron Microscopy (IEM) (1), Immunhistochemie (formalinfixierte Schnitte) (IHC (f)) (1)
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| Produktnummer |
ABIN141188 |
| Menge |
0.1 ml (Varianten) |
| Preis |
300,00 € Zzgl. Versandkosten €20,00 und MWSt
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| Lieferung nach |
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| Verfügbarkeit |
Lieferung in 7 bis 10 Werktagen |
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Weitere Bezeichnung
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DEDD2
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Format
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Serum
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Beschreibung
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A novel Death Effector Domain-containing protein, DEDD2, is closest in amino acid sequence homology to Death Effector Domain-containing DNA-binding protein, DEDD. DEDD2 is expressed widely in adult human tissues with highest levels in liver, kidney and peripheral blood leukocytes. DEDD2 interacts with FLIP, but not with FADD or Caspase 8. Over-expression of DEDD2 induces moderate apoptosis and results in substantial sensitization to apoptosis induced by Fas(CD95/APO-1), TRAIL(Apo2L), or FADD. These findings suggest that DEDD2 is involved in the regulation of nuclear events mediated by the extrinsic apoptosis pathway.
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Spezifität
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Reacts with residues 144-129 of the DEDD2 protein.
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Applikationshinweise
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Not tested. The investigator should determine the optimal dilution for a specific application such as immunohistochemistry.
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Reinheit
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Serum
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Buffer
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100 ul serum containing 0.02% sodium azide.
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Lagerung
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Maintain at +2-8 C for 3 months or at -20 C for longer periods. Stable for 1 year. Avoid repeated freeze-thaw cycles.
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Forschungsgebiet
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Apoptose/Nekrose, Todesrezeptoren
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Beschränkungen
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Nur für Forschungszwecke einsetzbar
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Alternativen zu Antigen "Death Effector Domain Containing 2 (DEDD2)", Typ "Antikörper" finden
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Wirte
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Kaninchen (35)
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Reaktivitäten
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Human (30), Maus (23), Ratte (Rattus) (22), Rind (Kuh) (10), Hund (9), Huhn (4), Kaninchen (4), Pferd (3), Schwein (2), Schaf (1)
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Applikationen
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Durchflusszytometrie (FACS) (17), Immunfluoreszenz (IF) (16), Western Blot (WB) (13), Immunhistochemie (Paraffinschnitte) (IHC (p)) (5), Immunpräzipitation (IP) (4), ELISA (3), Immunhistochemie (Gefrierschnitte) (IHC (fro)) (3), Dot Blot (Dot) (1), Enzyme Immunoassay (EIA) (1), Immunoelectron Microscopy (IEM) (1), Immunhistochemie (formalinfixierte Schnitte) (IHC (f)) (1)
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Konjugate
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Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1), RBITC (1)
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Alternativen 
