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V-Myc Myelocytomatosis Viral Oncogene Homolog (Avian) (MYC) (EQKLISEEDL) Antikörper
| Antigen | V-Myc Myelocytomatosis Viral Oncogene Homolog (Avian) (MYC) |
| Synonyme | MRTL, c-Myc, bHLHe39, MYC, CMYC, MGC138120, c-myc, C-MYC, LOC100136746 |
| Epitope |
Alternativen EQKLISEEDL |
| Klonalität | Polyklonal |
| Wirt |
Alternativen Maus |
| Reaktivität |
Alternativen Huhn, Human, Maus |
| Applikation |
Alternativen Immunhistochemie (Gefrierschnitte) (IHC (fro)), Enzyme Immunoassay (EIA), Immunpräzipitation (IP), Immunhistochemie (Paraffinschnitte) (IHC (p)), Western Blot (WB)
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| Produktnummer | ABIN139700 |
| Menge | 0.1 mg (0.50-1.00 mg/ml (batch dependent)) |
| Preis | 320,00 € Zzgl. Versandkosten €20,00 und MWSt |
| Lieferung nach |
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| Verfügbarkeit | Lieferung in 7 bis 10 Werktagen |
Produktbeschreibung
| Weitere Bezeichnung | C-Myc Epitope Tag (EQKLISEEDL) |
| Immunogen | Synthetic peptide AEEQKLISEEDL (aa 408-420) of human c-myc coupled to KLH |
| Isotyp | IgG2a (Passende Sekundärantikörper) |
| Beschreibung | The c-Myc protein is a transcription factor, which is encoded by the c-Myc gene on human chromosome 8q24. c-Myc is commonly activated in a variety of tumor cells and plays an important role in cellular proliferation, differentiation, apoptosis and cell cycle progression. The phosphorylation of c-Myc has been investigated and previous studies have suggested a functional association between phosphorylation at Thr58/Ser62 by glycogen synthase kinase 3, cyclin-dependent kinase, ERK2 and C-Jun N-terminal Kinase (JNK) in cell proliferation and cell cycle regulation. Studies also have shown that c-Myc is essential for tumor cell development in vasculogenesis and angiogenesis that distribute blood throughout the cells, and which brought extensive attention in the development of new therapeutic approach for cancer treatment. |
Anwendungen
| Applikationshinweise | Suggested working dilutions: Immunoprecipitation: 2 ug/mg protein lysate, Western blotting: 1:500-1:1000, Not tested in other applications. Optimal dilutions/concentrations should be determined by the end user |
| Konzentration | 0.50-1.00 mg/ml (batch dependent) |
| Reinheit | Protein A purified |
| Buffer | Phosphate-buffered saline |
| Lagerung | Store at 4C. Long term (>6months) aliquot and store at -20C. Avoid repeated freeze thawing.  , Primary Antibodies |
| Forschungsgebiet | Transkriptionsfaktoren, Tags/Labels |
| Beschränkungen | Nur für Forschungszwecke einsetzbar |
Alternativen
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