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COQ10B Antikörper (AA 38-110) (Alexa Fluor 488)

COQ10B Reaktivität: Human, Maus WB, IF (cc), IF (p) Wirt: Kaninchen Polyclonal Alexa Fluor 488
Produktnummer ABIN1392562
  • Target Alle COQ10B Antikörper anzeigen
    COQ10B (Coenzyme Q10 Homolog B (COQ10B))
    Bindungsspezifität
    • 14
    • 1
    • 1
    AA 38-110
    Reaktivität
    • 18
    • 16
    • 2
    Human, Maus
    Wirt
    • 18
    • 1
    Kaninchen
    Klonalität
    • 18
    • 1
    Polyklonal
    Konjugat
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser COQ10B Antikörper ist konjugiert mit Alexa Fluor 488
    Applikation
    • 18
    • 12
    • 12
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Spezifität
    Cross-reactivity with COQ10A (91 % homology with the immunogen sequence),
    Kreuzreaktivität
    Human, Maus
    Homologie
    Rat,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human COQ10B
    Isotyp
    IgG
    Top Product
    Discover our top product COQ10B Primärantikörper
  • Applikationshinweise
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    COQ10B (Coenzyme Q10 Homolog B (COQ10B))
    Andere Bezeichnung
    COQ10B (COQ10B Produkte)
    Synonyme
    1500041J02Rik antikoerper, 1700030I21Rik antikoerper, 9530077A17Rik antikoerper, AV002237 antikoerper, AW742641 antikoerper, RGD1359509 antikoerper, fc38f07 antikoerper, im:6912267 antikoerper, wu:fc38f07 antikoerper, zgc:112103 antikoerper, coenzyme Q10B antikoerper, COQ10B antikoerper, Coq10b antikoerper, coq10b antikoerper
    Hintergrund

    Synonyms: Coenzyme Q10, Coenzyme Q10 B, Coenzyme Q10 homolog B, Coenzyme Q10B, CQ10B_HUMAN.

    Background: COQ10B, Coenzyme Q10, is a 247 amino acid protein encoded by the human gene COQ10B. COQ10B is a mitochondrial protein that belongs to the COQ10 family. COQ10B is an essential biological cofactor which increases brain mitochondrial concentration and exerts neuroprotective effects. Plasma COQ10B levels decrease in patients with advanced chronic heart failure (CHF) while COQ10B levels in hyperthyroid patients are found among the lowest detected in human diseases. Likewise, COQ10B is elevated in hypothyroid subjects, also in subclinical conditions, suggesting the usefulness of this index in assessing metabolic status in thyroid disorders. It is believed that secretion of adrenal hormones is in some way related to COQ10B levels, both in augmented and reduced conditions. However, since thyroid hormones have an important role in modulating COQ10B levels and metabolism, when coexistent, thyroid deficiency seems to play a prevalent role in comparison with adrenal deficiency.

    Gen-ID
    80219
    UniProt
    Q9H8M1
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