Angiogenin, Ribonuclease, RNase A Family, 5 (ANG) Antikörper

Antigen: Angiogenin, Ribonuclease, RNase A Family, 5 (ANG)

Synonyme: ALS9, HEL168, RNASE4, RNASE5, MGC22466, MGC71966, ANG1

Klonalität: Polyklonal

Wirt: Maus

Reaktivität: Human

Applikation: Enzyme Immunoassay (EIA), Western Blot (WB)

Produktnummer: ABIN139015

Produktbeschreibung

Weitere Bezeichnung: Angiogenin

Immunogen: Recombinant full length protein (Human)

Isotyp: IgG1  (Passende Sekundärantikörper)

Beschreibung: Angiogenin is a member of the ribonuclease superfamily with approximately 35% amino acid sequence identity with pancreatic RNase. Like other members of the ribonuclease superfamily, angiogenin is a cytotoxic agent that can eliminate cellular protein synthesis. Angiogenin causes protein synthesis inhibition by functioning as a cytotoxic tRNA-specific RNase. Angiogenesis is the formation of blood vessels or capillaries from existing blood vessels due to specific signals. Angiogenin induces the growth of new blood vessels. It stimulates capillary and umbilical vein endothelial cells to produce diacylglycerol and secrete prostacyclin by phospholipase activation. Angiogenin exhibits both angiogenic and non-angiogenic activities and is involved in endothelial cell migration, proliferation, and differentiation. It is produced by a variety of tumor and normal cell types. Cells that express angiogenin include vascular endothelial and smooth muscle cells, fibroblasts, normal colonic epitheliu

Anwendungen

Applikationshinweise: ELISA: Use at a concentration of 1-2 ug/ml. WB: Use at a concentration of 1-2 ug/ml. Detects a band of approximately 14.4 kDa. Not tested in other applications. Optimal dilutions/concentrations should be determined by the end user.

Konzentration: 0.5 mg/ml

Reinheit: Protein G purified

Buffer: Phosphate-buffered saline

Lagerung: Keep as concentrated solution. Aliquot and store at -20?C or below. Avoid freeze-thaw cycles.

Forschungsgebiet: Zytokine

Beschränkungen: Nur für Forschungszwecke einsetzbar