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CACNA1S Antikörper (AA 951-1001)

CACNA1S Reaktivität: Human, Maus, Ratte ELISA, IF (cc), IF (p), IHC (p) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN1387901
  • Target Alle CACNA1S Antikörper anzeigen
    CACNA1S (Calcium Channel, Voltage-Dependent, L Type, alpha 1S Subunit (CACNA1S))
    Bindungsspezifität
    • 14
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 951-1001
    Reaktivität
    Human, Maus, Ratte
    Wirt
    • 22
    • 2
    Kaninchen
    Klonalität
    • 23
    • 1
    Polyklonal
    Konjugat
    • 10
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CACNA1S Antikörper ist unkonjugiert
    Applikation
    • 12
    • 12
    • 9
    • 6
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Kreuzreaktivität
    Human, Maus, Ratte
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human CACNA1S
    Isotyp
    IgG
  • Applikationshinweise
    ELISA 1:500-1000
    IHC-P 1:200-400
    IF(IHC-P) 1:50-200
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Haltbarkeit
    12 months
  • Lobeck, Donnelly, Dupree, Mahe, McNeal, Mohanty, Tiao: "Rhesus rotavirus VP6 regulates ERK-dependent calcium influx in cholangiocytes." in: Virology, Vol. 499, pp. 185-195, (2016) (PubMed).

  • Target
    CACNA1S (Calcium Channel, Voltage-Dependent, L Type, alpha 1S Subunit (CACNA1S))
    Andere Bezeichnung
    CACNA1S (CACNA1S Produkte)
    Synonyme
    CACNA1S antikoerper, cav1.1 antikoerper, ca(v)1.1 antikoerper, CACNL1A3 antikoerper, CCHL1A3 antikoerper, Cav1.1 antikoerper, HOKPP antikoerper, HOKPP1 antikoerper, MHS5 antikoerper, TTPP1 antikoerper, hypoPP antikoerper, AW493108 antikoerper, Cchl1a3 antikoerper, fmd antikoerper, mdg antikoerper, sj antikoerper, caV1.1 antikoerper, calcium voltage-gated channel subunit alpha1 S antikoerper, calcium channel, voltage-dependent, L type, alpha 1S subunit S homeolog antikoerper, calcium channel, voltage-dependent, L type, alpha 1S subunit antikoerper, CACNA1S antikoerper, cacna1s.S antikoerper, Cacna1s antikoerper
    Hintergrund

    Synonyms: Voltage-dependent L-type calcium channel subunit alpha-1S, Calcium channel, L type, alpha-1 polypeptide, isoform 3, skeletal muscle, Voltage-gated calcium channel subunit alpha Cav1.1, CACNA1S, CACH1, CACN1, CACNL1A3

    Background: Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1S gives rise to L-type calcium currents. Long-lasting (L-type) calcium channels belong to the 'high-voltage activated' (HVA) group. They are blocked by dihydropyridines (DHP), phenylalkylamines, benzothiazepines, and by omega-agatoxin-IIIA (omega-Aga-IIIA). They are however insensitive to omega-conotoxin-GVIA (omega-CTx-GVIA) and omega-agatoxin-IVA (omega-Aga-IVA). Calcium channels containing the alpha-1S subunit play an important role in excitation-contraction coupling in skeletal muscle.

    Gen-ID
    779
    UniProt
    Q13698
    Pathways
    Skeletal Muscle Fiber Development
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