HSPB7 Antikörper (AA 135-170)

Produktnummer ABIN1387071

Produktdetails anti-HSPB7 Antikörper

Target: HSPB7 (Heat Shock 27kDa Protein Family, Member 7 (Cardiovascular) (HSPB7))

Bindungsspezifität: AA 135-170

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HSPB7 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human HSPB7/cvHSP

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400
IF(IHC-P) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu HSPB7

Target: HSPB7 (Heat Shock 27kDa Protein Family, Member 7 (Cardiovascular) (HSPB7))

Andere Bezeichnung: HSPB7 (HSPB7 Produkte)

Synonyme: hspb7 antikoerper, MGC83758 antikoerper, HSPB7 antikoerper, cvhsp antikoerper, cvHSP antikoerper, 27kDa antikoerper, Hsp25-2 antikoerper, cvHsp antikoerper, heat shock protein family B (small) member 7 L homeolog antikoerper, heat shock protein family B (small) member 7 antikoerper, heat shock protein family, member 7 (cardiovascular) antikoerper, hspb7.L antikoerper, HSPB7 antikoerper, hspb7 antikoerper, Hspb7 antikoerper

Hintergrund:

Synonyms: cvHSP, Heat shock protein beta-7, HspB7, Cardiovascular heat shock protein

Background: The heat shock proteins (HSPs) comprise a group of highly conserved, abundantly expressed proteins with diverse functions, including the assembly and sequestering of multiprotein complexes, transportation of nascent polypeptide chains across cellular membranes and regulation of protein folding. Heat shock proteins (also known as molecular chaperones) fall into six general families: HSP 90, HSP 70, HSP 60, the small HSPs, the immunophilins and the HSP 110 family. HSPB7 (heat shock 27 kDa protein family, member 7), also known as cvHSP (cardiovascular heat shock protein) or Heat shock protein beta-7, is a member of the small HSP (sHSP) family expressed in heart and skeletal muscle. Members of the sHSP family contain a conserved C-terminal ?crystallin domain and typically function in homo- or heteromeric complexes. The sHSPs bind to denatured proteins and are responsible for preventing the aggregation of these proteins. In response to muscle fiber transformation and in muscular dystrophy, the expression levels of HSPB7 are drastically increased, suggesting that HSPB7 may be a useful target in therapeutic strategies for preventing age-related muscle wasting.

Gen-ID: 27129

UniProt: Q9UBY9