MYLK Antikörper (AA 651-750)

Produktnummer ABIN1386218

Produktdetails anti-MYLK Antikörper

Target: MYLK (Myosin Light Chain Kinase (MYLK))

Bindungsspezifität: AA 651-750

Reaktivität: Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MYLK Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Kreuzreaktivität: Ratte

Homologie: Human,Mouse,Dog,Cow,Sheep,Pig,Horse,Chicken,Guinea Pig

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human MLCK

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu MYLK

Target: MYLK (Myosin Light Chain Kinase (MYLK))

Andere Bezeichnung: MLCK (MYLK Produkte)

Synonyme: AAT7 antikoerper, KRP antikoerper, MLCK antikoerper, MLCK1 antikoerper, MLCK108 antikoerper, MLCK210 antikoerper, MSTP083 antikoerper, MYLK1 antikoerper, smMLCK antikoerper, 9530072E15Rik antikoerper, A930019C19Rik antikoerper, AW489456 antikoerper, Mlck antikoerper, SMMLCK antikoerper, mlck antikoerper, fj60a06 antikoerper, mlck1a antikoerper, mylk antikoerper, wu:fj60a06 antikoerper, zmlck1 antikoerper, myosin light chain kinase antikoerper, myosin, light polypeptide kinase antikoerper, myosin, light chain kinase a antikoerper, MYLK antikoerper, Mylk antikoerper, mylka antikoerper

Hintergrund:

Synonyms: KRP, AAT7, MLCK, MLCK1, MYLK1, s mMLCK, MLCK108, MLCK210, MSTP083, Myosin light chain kinase, smooth muscle, Kinase-related protein, Telokin, MYLK

Background: This gene, a muscle member of the immunoglobulin gene superfamily, encodes myosin light chain kinase which is a calcium/calmodulin dependent enzyme. This kinase phosphorylates myosin regulatory light chains to facilitate myosin interaction with actin filaments to produce contractile activity. This gene encodes both smooth muscle and nonmuscle isoforms. In addition, using a separate promoter in an intron in the 3' region, it encodes telokin, a small protein identical in sequence to the C-terminus of myosin light chain kinase, that is independently expressed in smooth muscle and functions to stabilize unphosphorylated myosin filaments. A pseudogene is located on the p arm of chromosome 3. Four transcript variants that produce four isoforms of the calcium/calmodulin dependent enzyme have been identified as well as two transcripts that produce two isoforms of telokin. Additional variants have been identified but lack full length transcripts. [provided by RefSeq, Jul 2008]

Gen-ID: 4638

UniProt: Q15746