TXNRD1 Antikörper (AA 451-550)

Produktnummer ABIN1386102

Produktdetails anti-TXNRD1 Antikörper

Target: TXNRD1 (Thioredoxin Reductase 1 (TXNRD1))

Bindungsspezifität: AA 451-550

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TXNRD1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Kreuzreaktivität: Human, Maus, Ratte

Homologie: Dog,Cow,Pig,Horse

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human TXNRD1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Referenzen für anti-TXNRD1 Antikörper (ABIN1386102)

Kaya, Çiçek, Erdi, Findik, Karatas, Esen, Keskin, Kalkan: "Intratumoral hemorrhage-related differences in the expression of vascular endothelial growth factor, basic fibroblast growth factor and thioredoxin reductase 1 in human glioblastoma." in: Molecular and clinical oncology, Vol. 5, Issue 4, pp. 343-346, (2016) (PubMed).

Details zu TXNRD1

Target: TXNRD1 (Thioredoxin Reductase 1 (TXNRD1))

Andere Bezeichnung: Txnrd1 (TXNRD1 Produkte)

Synonyme: TrxR1 antikoerper, cb682 antikoerper, fb83a08 antikoerper, wu:fb83a08 antikoerper, GB14972 antikoerper, MGC85342 antikoerper, NADPH-dependent thioredoxin reductase C antikoerper, T32G6.20 antikoerper, T32G6_20 antikoerper, GRIM-12 antikoerper, TR antikoerper, TR1 antikoerper, TRXR1 antikoerper, TXNR antikoerper, Tr antikoerper, thioredoxin reductase 1 antikoerper, thioredoxin reductase 1 L homeolog antikoerper, NADPH-dependent thioredoxin reductase C antikoerper, ThioRedoXin Reductase antikoerper, TXNRD1 antikoerper, txnrd1 antikoerper, Trxr-1 antikoerper, txnrd1.L antikoerper, NTRC antikoerper, trxr-1 antikoerper, Txnrd1 antikoerper

Hintergrund:

Synonyms: TR, TR1, TXNR, TRXR1, GRIM-12, Thioredoxin reductase 1, cytoplasmic, Gene associated with retinoic and interferon-induced mortality 12 protein, Gene associated with retinoic and IFN-induced mortality 12 protein, KM-12-derived reductase-like factor, Thioredoxin reductase TR1, TXNRD1, GRIM12, KDRF

Background: Isoform 1 may possess glutaredoxin activity as well as thioredoxin reductase activity and induces actin and tubulin polymerization, leading to formation of cell membrane protrusions. Isoform 4 enhances the transcriptional activity of estrogen receptors alpha and beta while isoform 5 enhances the transcriptional activity of the beta receptor only. Isoform 5 also mediates cell death induced by a combination of interferon-beta and retinoic acid.

Gen-ID: 7296

UniProt: Q16881

Pathways: Regulation of Lipid Metabolism by PPARalpha, Regulation of Carbohydrate Metabolic Process, Cell RedoxHomeostasis