Fibrinogen (Fbg) Antikörper
| Antigen |
|
| Synonyme |
fib2, MGC53620, fibrinogen, Fib, ENSMUSG00000059807, Fba5e, Ac1873, MGC156536, sb:cb892, zgc:92117, wu:fa55c12, wu:fi39d04, FGA, MGC128011 |
| Klonalität |
Polyklonal |
|
Wirt
|
|
|
Reaktivität
|
|
|
Applikation
|
Western Blot (WB) (173), ELISA (140), Immunfluoreszenz (IF) (124), Durchflusszytometrie (FACS) (90), Enzyme Immunoassay (EIA) (88), Immunpräzipitation (IP) (49), Immunodiffusion (ID) (33), Immunhistochemie (Paraffinschnitte) (IHC (p)) (32), Radioimmunoassay (RIA) (31), Immunhistochemie (Gefrierschnitte) (IHC (fro)) (22), ELISA (Detektionsantikörper) (20), Immunhistochemie (formalinfixierte Schnitte) (IHC (f)) (19), Immunhistochemie (IHC) (18), Immunelektrophorese (IEP) (13), Immunzytochemie (ICC) (11), Radiale Immunodiffusion (RID) (9), Dot Blot (Dot) (8), To be determined by user (TBD) (7), Immunoelectron Microscopy (IEM) (6), ELISA (Fangantikörper) (5), Magnetbeads (MB) (4), Affinitätschromatographie (AC) (1), Blocking Antibody (Inhibition) (1), Funktionale Studien (Func) (1), Gel Shift (GS) (1), Immunelektronenmikroskopie (EM) (1), Turbidimetrie (Trübungsmessung) (IT) (1), Nephelometrie (Neph) (1), Ouchterlony Double Diffusion (ODD) (1)
|
| Produktnummer |
ABIN138237 |
| Menge |
0.1 mg (Batch Dependent) (Varianten) |
| Preis |
240,00 € Zzgl. Versandkosten €20,00 und MWSt
|
| Lieferung nach |
|
| Verfügbarkeit |
Lieferung in 7 bis 10 Werktagen |
|
Weitere Bezeichnung
|
Fibrinogen
|
|
Immunogen
|
Fibrin degradation products
|
|
Isotyp
|
IgG1 (Passende Sekundärantikörper)
|
|
Beschreibung
|
Fibrinogen is the main protein of blood coagulation system. It is a large protein (MW 340 kDa) and it consists of two identical subunits that contain three polypeptide chains: alpha, beta and gamma. All chains are connected with each other by a number of disulfide bonds. Fibrinopeptides A (1-16 amino acids) and B (1-17 amino acids) are released by thrombin from the N-terminal parts of alpha- and beta-chains, respectively. In this way fibrinogen is converted into fibrin, which by means of polymerization forms a fibrin clot. Fibrinogen clotting underlies pathogenesis of MI, thromboembolism and thromboses of arteries and veins, since fibrin is the main substrate for thrombus formation. Fibrinogen activation is also involved in pathogenesis of inflammation, tumor growth and many other diseases.
|
|
Spezifität
|
Fibrinogen, Fibrin degradation products
|
|
Applikationshinweise
|
ELISA: Use at an assay dependent dilution. WB: Use at an assay dependent dilution. Can be paired for ELISA with ABIN138234 Mouse monoclonal [27C8] to Fibrinogen as detection and ABIN137192 Mouse monoclonal [40F11] to Fibrinogen as capture. Not tested in other applications. Optimal dilutions/concentrations should be determined by the end user.
|
|
Konzentration
|
Batch Dependent
|
|
Reinheit
|
Protein A purified
|
|
Buffer
|
Phosphate-buffered saline, pH7.4, containing 0.1% sodium azide
|
|
Lagerung
|
Keep as concentrated solution, aliquot and store at 4C. Do not freeze.
|
|
Forschungsgebiet
|
Kardiovaskuläres System, Artherosklerose, Extrazelluläre Matrix, Gerinnung
|
|
Beschränkungen
|
Nur für Forschungszwecke einsetzbar
|
Alternativen zu Antigen "Fibrinogen (Fbg)", Typ "Antikörper" finden
|
Wirte
|
Kaninchen (134), Maus (96), Ziege (94), Schaf (53), Huhn (7), Ratte (2)
|
|
Reaktivitäten
|
Human (251), Maus (37), Kaninchen (25), Ratte (Rattus) (24), Hund (14), Schwein (9), Rind (Kuh) (4), Schaf (1)
|
|
Applikationen
|
Western Blot (WB) (173), ELISA (140), Immunfluoreszenz (IF) (124), Durchflusszytometrie (FACS) (90), Enzyme Immunoassay (EIA) (88), Immunpräzipitation (IP) (49), Immunodiffusion (ID) (33), Immunhistochemie (Paraffinschnitte) (IHC (p)) (32), Radioimmunoassay (RIA) (31), Immunhistochemie (Gefrierschnitte) (IHC (fro)) (22), ELISA (Detektionsantikörper) (20), Immunhistochemie (formalinfixierte Schnitte) (IHC (f)) (19), Immunhistochemie (IHC) (18), Immunelektrophorese (IEP) (13), Immunzytochemie (ICC) (11), Radiale Immunodiffusion (RID) (9), Dot Blot (Dot) (8), To be determined by user (TBD) (7), Immunoelectron Microscopy (IEM) (6), ELISA (Fangantikörper) (5), Magnetbeads (MB) (4), Affinitätschromatographie (AC) (1), Blocking Antibody (Inhibition) (1), Funktionale Studien (Func) (1), Gel Shift (GS) (1), Immunelektronenmikroskopie (EM) (1), Turbidimetrie (Trübungsmessung) (IT) (1), Nephelometrie (Neph) (1), Ouchterlony Double Diffusion (ODD) (1)
|
|
Konjugate
|
HRP (37), Biotin (36), FITC (29), Gold (7), Cy3 (6), Cy5 (6), Cy5.5 (6), PE (6), PE,Cy3 (6), PE,Cy5 (6), Alexa Flour 488 (5), Cy7 (5), PE,Cy7 (5), RBITC (5), Alexa Fluor 488 (4), Alexa Fluor 350 (3), Alexa Fluor 555 (3), Alexa Fluor 647 (3), PE,Cy5.5 (3)
|
|
Epitope
|
Insoluble Fraction Oxidized (2), Oxidized Soluble Fraction (2), Total Fraction Oxidised (2)
|
Alternativen 
